采用液液萃取高效液相色谱法同时测定水基胶中17种邻苯二甲酸酯类物质的残留量。水基胶样品经水分散后,用乙酸乙酯萃取,萃取液离心后,取上层清液过0.45 μm有机相滤膜。以DIONEX Acclaim explosives E2柱为分离柱,以不同体积比的乙腈和水的混合溶液为流动相进行梯度洗脱,在检测波长220 nm处进行测定。17种邻苯二甲酸酯的质量浓度均在0.4~20.0 mg·L-1范围内与峰面积呈线性关系,方法的检出限(3s)在0.024~0.114 mg·L-1之间,测定下限(10s)在0.079~0.379 mg·L-1之间。加标回收率在89.7%~101%之间,测定值的相对标准偏差(n=5)小于6.0%。

HPLC was applied to the simultaneous determination of residual amounts of 17 phthalates in waterbased adhesives with liquidliquid extraction. After dispersed in water, the sample was extracted by ethyl acetate. The extract was centrifuged and the supernatant was filtered on 0.45 μm organic filtering membrane. DIONEX Acclaim explosives E2 column was used as stationary phase for separation, and mixtures of acetonitrile and water in different ratios were used as mobile phase in the gradient elution. UVdetection at 220 nm was adopted in the determination. Linear relationships between values of peak area and mass concentration of the 17 phthalates were kept in the same range of 0.4-20.0 mg·L-1, with detection limits (3s) in the range of 0.024-0.114 mg·L-1 and lower limits of determination (10s) in the range of 0.079-0.379 mg·L-1. Values of recovery found by standard addition method were in the range of 89.7%-101%, and values of RSD′s (n=5) less than 6.0%.