镁锌合金骨螺钉表面防降解改性涂层的制备与性能
Preparation and Properties of Modified Anti-degradation Coating on the Surface of Mg-Zn Alloy Bone Screws
摘 要
采用电化学沉积方法在镁锌合金骨螺钉表面制备了无氟和含氟(FHA)的钙磷盐防降解涂层, 并在模拟人体体液中进行体外降解试验, 采用扫描电镜和X射线衍射仪等分析了降解前后涂层的形貌与晶体结构。结果表明: 无氟涂层为丝状和块状结构, 而含氟涂层为柱状结构; 无氟和FHA钙磷盐涂层都可以有效减缓镁合金在模拟人体体液中的腐蚀, 前者比后者的效果更佳; FHA涂层不易溶解, 但与外形复杂的螺钉结合不牢, 且其质脆, 浸泡过程中易于脱落; 无氟涂层则能保持完整性, 可以对骨螺钉起到更好的保护作用。
骨螺钉
降解
钙磷盐涂层
Mg-Zn alloy
bone screw
degradation
Ca-P coating
Abstract
The anti-degradation coatings of Ca-P with or without F on the surface of Mg-Zn alloy bone screws were prepared by the method of electro-deposition. In vitro degradation of these screws in simulated body fluid (SBF) was investigated. The morphology and the crystal structure before and after degradation of the two kinds of Ca-P coatings were researched by scanning electronic microscope (SEM) and X-ray diffraction (XRD). The results showed that the surface of the Ca-P coating without F contained lumpish and filamentous structure, while that of the coating with F was columnar. The coatings with or without F can both retard the corrosion of the screw effectively. The screws coated with FHA degraded faster than the screws coated with the coating without F. The FHA coating was resistant to the corrosion. However it couldn′t combine quite well with the complex-shaped screw, coupled with its brittleness, and it tended to peel off. In contrast, the screws with the coating without F maintained integrity, which protect the bone screws effectively.
中图分类号 TG146.2
所属栏目 材料性能及其应用
基金项目 国家基础研究(973)计划项目(2012CB619102); 国家自然科学基金资助项目(51271117); 上海市骨科内植物重点实验室开放基金资助项目(KFKT2011002)
收稿日期 2012/1/27
修改稿日期 2012/11/7
网络出版日期
作者单位点击查看
备注王红菊(1986―), 女, 天津人, 硕士研究生。
引用该论文: WANG Hong-ju,LI Xiao,ZHANG Pei,ZHAO Chang-li,ZHANG Xiao-nong. Preparation and Properties of Modified Anti-degradation Coating on the Surface of Mg-Zn Alloy Bone Screws[J]. Materials for mechancial engineering, 2013, 37(2): 66～70
王红菊,李霄,张培,赵常利,张小农. 镁锌合金骨螺钉表面防降解改性涂层的制备与性能[J]. 机械工程材料, 2013, 37(2): 66～70
被引情况:
【1】李春梅,卫中领,吴森,周邦新, "镁合金AZ31表面含硅涂层在人工血浆中的降解行为",腐蚀与防护 35, 675-678(2014)
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【6】吴茂江. 镁与人体健康[J]. 微量元素与健康研究, 2006, 23(2): 65-66.
【7】MUELLER W D, NASCIMENTO M L, LORENZO DE MELE M F. Critical discussion of the results from different corrosion studies of Mg and Mg alloys for biomaterial applications[J].Acta Biomaterialia, 2010, 6(5): 1749-1755.
【8】SONG G. Control of biodegradation of biocompatible magnesium alloys[J].Corros Sci, 2007, 49(4): 1696-701.
【9】MANI G, FELDMAN M D, PATEL D, et al. Coronary stents: a materials perspective[J].Biomaterials, 2007, 28(9): 1689-1710.
【10】SONG Y W, SHAN DY, HAN E H. Electrodeposition of hydroxyapatite coating on AZ91D magnesium alloy for biomaterial application[J]. Mater Lett, 2008, 62(17/18): 3276-3279.
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【14】SONG Y, ZHANG S X, LI J N, et al. Electrodeposition of Ca-P coatings on biodegradable Mg alloy: In vitro biomineralization behavior[J].Acta Biomaterialia, 2010, 6(5): 1736-1742.
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【16】ZHANG S X, LI J N, SONG Y, et al. In vitro degradation, hemolysis, and MC3T3-E1 cell adhesion of biodegradable Mg-Zn alloy[J]. Mater Sci Eng C, 2009, 29(6): 1907-1912.
【17】OYANE A, KIM H M, FURUYA T, et al. Preparation and assessment of revised simulated body fluids[J].J Biomed Mater Res A, 2003, 65(2): 188-195.
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