125I种子源源芯制备工艺的改进
Modification of Technology of Preparation of Core-Source of 125I Seed Source
摘 要
对125I种子源制备过程中的关键工艺——源芯制备工艺进行了改进,采用将银丝预镀钯层后再进行125I吸附的方法制备125I种子源源芯。用1.0 g·L-1氯化钯溶液0.1 mL作为镀液;溶液中氯化钯与氯化氢的物质的量比为1比1。经紫外分光光度法测定,每根银丝上钯的饱和量为0.2 mg,对碘的吸附率约为94%。经扫描电镜和X光电子能谱表征可知,银丝表面成功地吸附了单质碘,该吸附为物理吸附。
吸附
种子源
125I
Adsorption
Seed source
Abstract
The key technology in preparation of source core of 125I seed source was modified by plating Pd on the surface of Ag wire and then using it to adsorb 125I. One tenth mL of 1.0 g·L-1 PdCl2 solution containing HCl with mole ratio between PdCl2 and HCl of 1 to 1 was used for the plating. Values of saturation capacity of Pd on the surface of Ag wire was attained to 0.2 mg and rate of adsorption against I was attained to about 94% as determined by UV spectrophotometry. It was found that iodine was adsorbed successfully on the surface of Pd-plated Ag wire as characterized by scanning electron microscope and X ray photoelectron spectroscopy, and the adsorption was proved to be physical adsorption.
中图分类号 O614.7
所属栏目 工作简报
基金项目 中国工程物理研究院军民两用基金资助项目(200909);中国工程物理研究院科学技术发展基金资助项目(2009B0301028)
收稿日期 2011/12/6
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备注何佳恒(1976-),女,四川广元人,副研究员,硕士,主要从事放射化学研究。
引用该论文: HE Jia-heng,JIANG Lin,WANG Jing,MA Zong-ping,ZHONG Wen-bin,DANG Yu-feng,JIAN Yuan. Modification of Technology of Preparation of Core-Source of 125I Seed Source[J]. Physical Testing and Chemical Analysis part B:Chemical Analysis, 2013, 49(2): 164～167
何佳恒,姜林,王静,马宗平,钟文彬,党宇峰,蹇源. 125I种子源源芯制备工艺的改进[J]. 理化检验－化学分册, 2013, 49(2): 164～167
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参考文献
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【3】XIE D Y, ZHANG Z C, LUO X Y. Permanent interstitial implantation of 125I seeds for 7 cases of malignant tumors［J］. Acad J Sec Mil Med Univ, 2000,21:174-176.
【4】MARTINEZ-MONGE R, NAG S, NIERODA C A, et al. Iodine-125 brachytherapy in the treatment of colorectal adenocarcinoma metastatic to the liver［J］. Cancer, 1999,85:1218-1225.
【5】ZELEFSKY M J. Intraoperative conformal optimizaton for transperineal prostate implantaton using magnetic resonance spectroscopic imaging［J］. Cancer J, 2000,6: 249-255.
【6】NATH R, MEIGOONI A S. A comparison of solid phantoms with water for dosimetry of I-125 and Ir-192 brachytherapy sources［J］. Med Phys, 1990,17:1032-1040.
【7】LING C C. Permanent implants using Au-198, Pd-103 and I-125: Radiobiological Considerations based on the linear quadratic model［J］. Int Radiat Oncol Biol Phys, 1992,23:81-87.
【8】NATH R, MEIGOONI A S, MUENCH P, et al . Anisotropy functions for Pd-103, I-125, and Ir-192 interstitial brachytherapy sources［J］. Med Phys, 1993,20:1465-1473.
【9】WILLIAMSON J F, QUITERO F J. Theortical evaluation of dose distribution about models 6711 and 6702 I-125 seeds［J］. Med Phys, 1988,15:891-897.
【10】山常起.CIZE-6711型I-125颗粒种子密封源［J］.现代临床医学生物工程学杂志, 2001(6):438-439.
【11】罗开元,李波,杨嵘,等.125I粒子组织间放射治疗恶性肿瘤的临床应用［J］.中华医学杂志, 2001,81(6):754-755.
【12】张冰,罗开元,张桂仙,等.125I籽永久性植入(组织间放疗)治疗癌症:附19例报告［J］.中国现代医学杂志, 2000(10):68-69.
【2】LI Z. An algorithm for automatic, computed-tomography-based source localization after prostate implant［J］. Med Phys, 2001,28:1410-1415.
【3】XIE D Y, ZHANG Z C, LUO X Y. Permanent interstitial implantation of 125I seeds for 7 cases of malignant tumors［J］. Acad J Sec Mil Med Univ, 2000,21:174-176.
【4】MARTINEZ-MONGE R, NAG S, NIERODA C A, et al. Iodine-125 brachytherapy in the treatment of colorectal adenocarcinoma metastatic to the liver［J］. Cancer, 1999,85:1218-1225.
【5】ZELEFSKY M J. Intraoperative conformal optimizaton for transperineal prostate implantaton using magnetic resonance spectroscopic imaging［J］. Cancer J, 2000,6: 249-255.
【6】NATH R, MEIGOONI A S. A comparison of solid phantoms with water for dosimetry of I-125 and Ir-192 brachytherapy sources［J］. Med Phys, 1990,17:1032-1040.
【7】LING C C. Permanent implants using Au-198, Pd-103 and I-125: Radiobiological Considerations based on the linear quadratic model［J］. Int Radiat Oncol Biol Phys, 1992,23:81-87.
【8】NATH R, MEIGOONI A S, MUENCH P, et al . Anisotropy functions for Pd-103, I-125, and Ir-192 interstitial brachytherapy sources［J］. Med Phys, 1993,20:1465-1473.
【9】WILLIAMSON J F, QUITERO F J. Theortical evaluation of dose distribution about models 6711 and 6702 I-125 seeds［J］. Med Phys, 1988,15:891-897.
【10】山常起.CIZE-6711型I-125颗粒种子密封源［J］.现代临床医学生物工程学杂志, 2001(6):438-439.
【11】罗开元,李波,杨嵘,等.125I粒子组织间放射治疗恶性肿瘤的临床应用［J］.中华医学杂志, 2001,81(6):754-755.
【12】张冰,罗开元,张桂仙,等.125I籽永久性植入(组织间放疗)治疗癌症:附19例报告［J］.中国现代医学杂志, 2000(10):68-69.
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