辅酶Q在CPT自组装修饰电极上的电化学行为及其分析应用
STUDY OF ELECTROCHEMICAL BEHAVIOR OF COENZYME Q AT THE CAPTOPRIL MODIFIED SELF-ASSEMBLED ELECTRODE AND ITS ANALYTICAL APPLICATION
摘 要
采用自组装方法制备了卡托普利(CPT)修饰电化学传感器,并对其在金电极表面形成的单分子膜进行了表征.循环伏安试验结果表明,辅酶Q在CPT修饰电极上能发生准可逆的电化学反应.该传感器对辅酶Q测定具有良好的响应,测定范围为5.0×10-6-6.0×10-5mol·L-1,检出限为2.0×10-6mol·L-1,异相电子传递速率常数ks为5.4×10-3cm·s-1.对CPT修饰膜的稳定性进行考察,讨论辅酶Q发生电化学反应的异相电子传递速率常数ks及其影响机制.
修饰电极
卡托普利
辅酶Q
电化学传感器
Self-assembling
Modified electrode
Captopril
Coenzyme Q
Electrochemical sensor
Abstract
An electrochemical sensor of captopril (CPT) modified,selfassembled Au-electrode was prepared,and the formation of mono-molecular membrane on the surface of Au-electrode was characterized.As shown by the results of the study of electrochemical behavior of coenzyme Q (CZM Q) at the CPT modified electrode,the electrode reaction was an one electrontransferring quasi-reversible reaction,and linear response in the concentration range of 5.0×10-6-6.0×10-5mol·L-1 of CZM Q was obtaioned,with a detection limit of 2.0×10-6mol·L-1.The constant of rate of heterogeneous electron-transfer (ks) was determined and its value calculated by the Nicholson method was 5.4×10-3cm·s-1,and the mechanism of factors affecting the value of ks of electrode reaction of CZM Q at the electrode was discussed.Conditions affecting the stability of the CPT modified electrode was also examined.
中图分类号 O657.1
所属栏目 试验与研究
基金项目 国家自然科学基金(No.20075023)和中国博士后基金资助项目
收稿日期 2005/7/2
修改稿日期
网络出版日期
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备注夏平宇(1973-),男,江苏常州人,工程师,宁波大学化学系访问学者,从事电化学传感器研究.
引用该论文: XIA Ping-yu,GAN Ning,GE Cong-xin. STUDY OF ELECTROCHEMICAL BEHAVIOR OF COENZYME Q AT THE CAPTOPRIL MODIFIED SELF-ASSEMBLED ELECTRODE AND ITS ANALYTICAL APPLICATION[J]. Physical Testing and Chemical Analysis part B:Chemical Analysis, 2006, 42(8): 604～607
夏平宇,干宁,葛从辛. 辅酶Q在CPT自组装修饰电极上的电化学行为及其分析应用[J]. 理化检验－化学分册, 2006, 42(8): 604～607
被引情况:
【1】杨怀成,曾金祥,魏万之, "电催化测定烟酰胺腺嘌呤二核苷酸-以聚亚甲基蓝-碳纳米管修饰电极作为工作电极",理化检验－化学分册 45, 533-536(2009)
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