L-苏氨酸与四氯对苯醌的荷移反应
Charge Transfer Reaction Between L-Threonine and Tetrachloro-p-Benzoquinone
摘 要
L-苏氨酸与四氯对苯醌发生荷移反应,建立一种测定L-苏氨酸新的光谱分析方法.在硼砂溶液中,L-苏氨酸与四氯对苯醌生成稳定的1∶1络合物,其λmax=220.3 nm,表观摩尔吸光系数ε=5.9×105L·mol-1·cm-1,在0.39~1.94 mg·L-1范围内符合比耳定律.药物样品L-苏氨酸含量,与文献方法测定结果一致,回收率为99.8%~100.3%,相对标准偏差在1%以内.该方法可用于药物分析.
分光光度法
L-苏氨酸
四氯对苯醌
Charge-transfer reaction
Spectrophotometry
L-threonine
Tetrachloro-p-benzoquinone
Abstract
In a borate buffer solution of pH 9.0,charge-transfer reaction between L-threonine and tetrachloro-p-benzoquinone was observed,and the complex formed had its absorption maxima at the wavelength of 220.3 nm and the value of its apparent molar absorptivity of 5.9×105L·mol-1·cm-1.Beer′s law was obeyed in the range of 0.39-1.94 mg·L-1 of L-threonine.This method was applied to the determination of L-threonine in samples of injection liquor,giving results in consistency with the results obtained by method in pharmacopoeia,and the value of RSD′s (n=9) found was less than 1%.Results of recovery test obtained by standard addition method were in the range of 99.8%-100.3%.
中图分类号 O657
所属栏目 工作简报
基金项目 天津师范大学自然科学青年基金资助项目
收稿日期 2006/5/14
修改稿日期
网络出版日期
作者单位点击查看
备注焦德权(1961-),女,山东人,硕士,主要从事分析化学教学与药物分析研究工作.
引用该论文: JIAO De-quan,LIU Er-bao. Charge Transfer Reaction Between L-Threonine and Tetrachloro-p-Benzoquinone[J]. Physical Testing and Chemical Analysis part B:Chemical Analysis, 2007, 43(3): 196～197
焦德权,刘二保. L-苏氨酸与四氯对苯醌的荷移反应[J]. 理化检验－化学分册, 2007, 43(3): 196～197
共有人对该论文发表了看法，其中：
人认为该论文很差
人认为该论文较差
人认为该论文一般
人认为该论文较好
人认为该论文很好
参考文献
【1】陈改荣,苗郁.磺胺胍与四氯苯醌的荷移反应[J].理化检验-化学分册,2003,39(9):535．
【2】冯喜兰,赵凤林,李 娜,等.氨基酸与四氰代苯醌二甲叉的荷移反应的研究[J].光谱学与光谱分析,2003,23(4):745．
【3】赵桂芝,李华侃.荷移分光光度法测定罗红霉素[J].光谱学与光谱分析,2003,23(1):157．
【4】李华侃,赵延清,王玉华,等.阿奇霉素与茜素的电荷转移反应及其测定[J].分析化学,2004,32(5):598．
【5】国家药典委员会.中华人民共和国药典(二部)[M].北京:化学工业出版社,2005:237．
【6】Darwish I A.Analytical study for the charge-transfer complexes of losartan potassium[J].Anal Chim Acta,2005,549:212．
【7】Moorthy P,Kathiresan K.UV-B induced alterations in composition of thylakoid membrane and amino acids in leaves of rhizophora apicalata blume[J].Photosynthetica,1998,35(3):321．
【8】周旭光.荷移反应及其在分析化学中的应用[J].分析化学,1993,21(2):184．
【2】冯喜兰,赵凤林,李 娜,等.氨基酸与四氰代苯醌二甲叉的荷移反应的研究[J].光谱学与光谱分析,2003,23(4):745．
【3】赵桂芝,李华侃.荷移分光光度法测定罗红霉素[J].光谱学与光谱分析,2003,23(1):157．
【4】李华侃,赵延清,王玉华,等.阿奇霉素与茜素的电荷转移反应及其测定[J].分析化学,2004,32(5):598．
【5】国家药典委员会.中华人民共和国药典(二部)[M].北京:化学工业出版社,2005:237．
【6】Darwish I A.Analytical study for the charge-transfer complexes of losartan potassium[J].Anal Chim Acta,2005,549:212．
【7】Moorthy P,Kathiresan K.UV-B induced alterations in composition of thylakoid membrane and amino acids in leaves of rhizophora apicalata blume[J].Photosynthetica,1998,35(3):321．
【8】周旭光.荷移反应及其在分析化学中的应用[J].分析化学,1993,21(2):184．
相关信息
