多壁碳纳米管修饰玻碳电极测定多贝斯
Determination of Calcium Dobesilate at Multi-walled Carbon Nanotube Modified Glassy Carbon Electrode
摘 要
制备了多壁碳纳米管修饰玻碳电极,研究发现:该修饰电极对多贝斯有良好的电催化作用,多贝斯在该修饰电极上出现了一对氧化还原峰,相对于裸玻碳电极,氧化还原峰电位差减至93 mV,提出了用循环伏安法测定多贝斯的方法.氧化峰电流与多贝斯的浓度在5.0×10-8~1.0×10-5mol·L-1范围内呈线性关系,检出限(3S/N)为2.0×10-8mol·L.
多贝斯
循环伏安法
电催化
Multi-walled carbon nanotubes
Calcium dobesilate
Cyclic voltammetry
Electrocatalysis
Abstract
Preparation of multi-walled carbon nanotube modified glassy carbon electrode (MWCNT′s/GCE) was reported in this paper.It was found that significant catalytic action of the MWCNT′s/GCE was observed on the reaction of calcium dobesilate (CD) at the electrode,showing a pair of oxidation and reduction peaks at the modified electrode,with potential difference of oxidation peak and reduction peak reduced to a value of 93 mV as compared with the reaction at the bare GCE.Base on these findings,a selective method for determination of CD by cyclic voltammetry was proposed.Linear relationship between values of oxidation peak current and concentration of CD was obtained in the ranges of 5.0×10-8-1.0×10-5,with detection limit (3S/N) of 2.0×10-8mol·L-1.
中图分类号 O657.1
所属栏目 工作简报
基金项目 榆林学院项目(08YK16)
收稿日期 2008/10/7
修改稿日期
网络出版日期
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备注张亚(1970-),女,陕西绥德人,副教授,主要研究方向为电分析化学与生物传感技术.
引用该论文: ZHANG Ya,ZHANG Zhi-fang. Determination of Calcium Dobesilate at Multi-walled Carbon Nanotube Modified Glassy Carbon Electrode[J]. Physical Testing and Chemical Analysis part B:Chemical Analysis, 2009, 45(11): 1296～1298
张亚,张智芳. 多壁碳纳米管修饰玻碳电极测定多贝斯[J]. 理化检验－化学分册, 2009, 45(11): 1296～1298
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参考文献
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【3】KRACMAR J,KRACMAVOVA J,KOVAROVA A,et al.UV spertrophotometry in drug control[J].Pharmazie,1988,43:173-178．
【4】汪海涛,董发昕,郎惠云.流动注射-抑制化学发光测定多贝斯的方法研究[J].分析试验室,2002,21(3):67-69．
【5】SONG Jun-feng,CHEN Jia-quan.Flow-injection biamperometric direct determination of calcium dobesilate in irreversible couple system[J].J Pharm Biomed Anal,2003,33:789-796．
【6】延绥宏,黑玉芬,吴少平,等.多贝斯的电化学行为及其测定[J].分析试验室,2004,23(3):4-7．
【7】SONG Zhen-hua,YUE Qiao-li,WANG Chang-na.Flow injection chemiluninescence for detecting pictogram amounts of dobesilate in human urine[J].Spectrochim Acta Part A,2004,60:2377-2382．
【8】IIJIMA S.Helical microtubules of graphitic carbon[J].Nature,1991,354(11):56-58．
【9】BAUGHMAN R H,ZAKHIDOV A A,HEER W A.Carbon namotubes the route toward applications[J].Science,2002,297:787-792．
【10】MUSTAFA Musameh,WANG Joseph,MERKOCL Arben,et al.Low-potential stable NADH detection at carbon-nanotube-modified glassy carbon electrodes[J].Electrochem Commun,2002,4:743-746．
【11】CAWREWCE Nathan,DEO Randhir P,WANG Joseph.Comparison of the electrochemical reactivity of electrodes modified with carbon nanotubes from different sources[J].Electroanalysis,2005,17:65-72．
【12】BRITTO P J,SANTHANAM K S V,AJAYAN P M.Carbon nanotube electrode for oxidation of dopamine[J].Bioelectrochem Bioenerg,1996,41:121-125．
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