用热解吸处理样品-气相色谱与质谱联用法建立烟用香精指纹图谱及其在烟用香精质量控制中的应用
Institution of Fingerprint Spectra of Tobacco Essence by Hyphenation of GC and MS with Thermal Desorption and Its Application to Quality Control of the Tobacco Essence
摘 要
采用热解吸-气相色谱-质谱法,建立了香精的指纹图谱,利用夹角余弦和欧式距离法计算相似度.结果表明:利用热脱附技术能够简化样品预处理过程,保证试验的重复性,为建立指纹图谱提供可靠的数据,并避免样品预处理过程中有效成分的损失以及高沸点物质对色谱仪器的污染.夹角余弦法和欧氏距离法计算简单,两者结合能够全面考察香精的质量.
气相色谱-质谱
香精
指纹图谱
相似度
Thermal desorption
Hyphenation of GC and MS
Essence
Fingerprint spectrum
Similarity
Abstract
The chromatographic fingerprint spectra of tobacco essence were instituted by hyphenation of GC and MS with thermal desorption,and the similarity was calculated by the methods of included angle cosine and Euclidean distance.It was shown that by applying the thermal desorption technique,not only the process of sample pretreatment was shortened and simplified,but also good repeatability of testing was attained,and thus to provide reliable data for the establishment of finger print spectra.Furthermore by using thermal desorption,loss of effective components during pretreatment of samples and pollution of the GC instrument by those high boiling-point substances were also prevented.And by the combination of the 2 easy calculation methods mentioned above,a comprehensive inspection on the quality of tobacco essence was attained.
中图分类号 O657.37
所属栏目 试验与研究
基金项目
收稿日期 2009/1/12
修改稿日期
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备注赵瑜(1981-),男,湖南邵东人,工程师,硕士,主要研究方向为烟用香精品质控制.
引用该论文: ZHAO Yu,YANG Hua-wu,ZHONG Ke-jun,LI Yan-chun,ZHU Zhuo-yue,CHEN Xiong,LI Yan-ling,SU Li-xia. Institution of Fingerprint Spectra of Tobacco Essence by Hyphenation of GC and MS with Thermal Desorption and Its Application to Quality Control of the Tobacco Essence[J]. Physical Testing and Chemical Analysis part B:Chemical Analysis, 2010, 46(2): 117～119
赵瑜,杨华武,钟科军,李燕春,朱卓越,陈雄,黎艳玲,苏利霞. 用热解吸处理样品-气相色谱与质谱联用法建立烟用香精指纹图谱及其在烟用香精质量控制中的应用[J]. 理化检验－化学分册, 2010, 46(2): 117～119
被引情况:
【1】金樱华,顾中怡,强音,程欲晓,杨勇,杜嘉琪, "热脱附-气相色谱-质谱法测定胶粘剂中苯系物的释放量",理化检验－化学分册 51, 1661-1665(2015)
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参考文献
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【3】李玉娟,王瑞,车镇涛,等.中药材指纹图谱质量控制方法研究[J].中药新药与临床药理,2001,2(3):192-195．
【4】谢培山.色谱指纹图谱分析是中草药质量控制的可行策略[J].中药新药与临床药理,2001,2(3):141-151．
【5】曲国福,陆舍铭,孟昭宇,等.色谱指纹图谱在烟用香精质量控制中的应用[J].烟草科技,2007(7):46-50．
【6】廖堃,胡纲,肖竞.烟用香精的高效液相色谱指纹图谱分析[J].烟草科技,2006(2):37-39．
【7】陈云霞,梁冰,王国俊.吸附浓缩/热脱附技术进展[J].分析测试技术与仪器,1999,5(1):3-14．
【8】MELCHER R G.Pump and tube (thermal Desorption)[J].Anal Chem,1983,55(5):40-50．
【9】李维翰,鲁玉珍.大气中挥发性苯系物的Carbotrap吸附气相色谱法[J].环境工程,1995,18(1):51-55．
【10】HEAVNER D L,OGDEN M W,NELSON P R.Multisorbent thermal desorption GC/ MS method for determination of target VOCS in indoorAir[J].Environ Sci & Technol,1992,26:1737-1746．
【11】谭培功,于彦彬.热脱附气相色谱-质谱联机定量分析气体中的亚磷酸三甲酯[J].分析化学,1996,24(1):116-118．
【12】WAMPLER T P,WASHALL J W,MATHESON M J.Applications of purge and trap to the analysis of beers[J].Am Lab,1996:18T-18U．
【13】陕生银.Tenax/吸附浓缩/热脱附气相色谱法监测分析车间空气中TDI[J].分析测试技术与仪器,1997,3(3):162-167．
【14】BROWN R H.What is the best sorbent for pumpedsampling-thermal desorption of VOCS[J].The Analyst,1996,121(9):1171-1175．
【15】蔡宝昌,刘训红.常用中药材HPLC指纹图谱测定技术[M].北京:化学工业出版社,2005:42．
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