通过改进的Hummers法和溶剂热法分别制备了石墨烯和硫化铜纳米花。采用滴涂法进一步依次将石墨烯和硫化铜纳米花修饰于玻碳电极，制备了硫化铜纳米花/石墨烯修饰玻碳电极（Nanoflower CuS/GR/GCE）。利用循环伏安法和差分脉冲伏安法等研究了长春地辛在该修饰电极的电化学行为。结果表明：长春地辛的浓度在1.0×10^-8~1.0×10^-7mol·L^-1，1.0×10^-7~1.1×10^-5mol·L^-1及1.1×10^-5~1.0×10^-4mol·L^-1内与其对应的峰电流的减小量呈线性关系，检出限（3S/N）为4.9×10^-9mol·L^-1。对1.0×10^-6mol·L^-1长春地辛标准溶液连续测定5次，测定值的相对标准偏差为1.2%。方法用于长春地辛药品样品的分析，加标回收率在97.1%~103%之间。

Graphene and CuS nanoflower were prepared respectively by modified Hummers method and solvothermal method. And then nanoflower CuS and graphen were coated by dropping successively onto the surface of glassy carbon electrode, to prepare the nanoflower CuS-graphene modified GCE (abbrev. as nanoflower CuS/GF/GCE). The electrochemical behavior of vindesine at this modified electrode was studied by cyclic voltametry and different pulse voltametry. It was found that linear relationship between the magnitude of decrease of oxidation peak current and concentration of vindesine was obtained in the ranges of 1.0×10^-8 to 1.0×10^-7mol·L^-1, 1.0×10^-7 to 1.1×10^-5mol·L^-1 and 1.1×10^-5 to 1.0×10^-4mol·L^-1, with detection limit (3S/N) of 4.9×10^-9mol·L^-1. Precision of the method was tested at the concentration of 1.0×10^-6mol·L^-1 vindesine standard solution for 5 determinations, value of RSD found was 1.2%. The proposed method was applied to the analysis of drug samples of vindesine, giving values of recovery in the range of 97.1%-103%.