金属有机骨架材料修饰玻碳电极循环伏安法测定维生素C片中抗坏血酸
Determination of Ascorbic Acid in Vitamin C Tablet by Cyclic Voltammetry at Glassy Carbon Electrode Modified with Metal Organic Framework
摘 要
合成了金属有机骨架材料（Zn-MOFs），通过电沉积方法将Zn-MOFs修饰到玻碳电极表面，制得Zn-MOFs修饰玻碳电极。采用循环伏安法在pH 5的磷酸盐缓冲溶液中以扫描速率100 mV·s-1对Zn-MOFs修饰玻碳电极进行表征。结果表明：相比于裸玻碳电极，Zn-MOFs修饰玻碳电极提高了抗坏血酸氧化活性。抗坏血酸的线性范围为4×10-5~1×10-2mol·L-1，方法的检出限（3s/k）为6.7×10-6mol·L-1。方法用于维生素C片样品的分析，加标回收率为91.0%~109%，测定值的相对标准偏差（n=5）为0.80%~1.9%。
金属有机骨架材料
修饰电极
抗坏血酸
维生素C片
cyclic voltammetry
metal organic framework
modified electrode
ascorbic acid
vitamin C tablet
Abstract
The metal organic framework (Zn-MOFs)was synthesized. Zn-MOFs was successfully modified to the glassy carbon electrode surface by electrodeposition method,and then the glassy carbon electrode modified with Zn-MOFs was prepared. The modified electrode was characterized by cyclic voltammetry in phosphate buffer solution of pH 5 at scanning rate of 100 mV·s-1. It was found that the modified electrode could improve the oxidation activity of ascorbic acid compared with bare glassy carbon electrode. Linearity range of ascorbic acid was found between 4×10-5mol·L-1 and 1×10-2mol·L-1 with detection limit (3s/k) of 6.7×10-6mol·L-1. The proposed method was applied to the analysis of samples of vitamin C tablet, giving values of recovery and RSD's (n=5) in the ranges of 91.0%-109% and 0.80%-1.9% respectively.
中图分类号 O657.1 DOI 10.11973/lhjy-hx201711004
所属栏目 工作简报
基金项目 “广西特聘专家”专项（N02401007012）；国家自然科学基金（21266006）；广西自然科学基金（2016GXNSFAA380109）
收稿日期 2016/11/14
修改稿日期
网络出版日期
作者单位点击查看
联系人作者刘峥(lisa4.6@163.com)
备注李庆伟(1990-),女,山东临沂人,硕士研究生,研究方向为功能有机合成
引用该论文: LI Qingwei,LIU Zheng,LI Haiying,GUO Zhengnan,WEI Xi,TANG Qun,ZHANG Shufen. Determination of Ascorbic Acid in Vitamin C Tablet by Cyclic Voltammetry at Glassy Carbon Electrode Modified with Metal Organic Framework[J]. Physical Testing and Chemical Analysis part B:Chemical Analysis, 2017, 53(11): 1259～1264
李庆伟,刘峥,李海莹,郭征楠,魏席,唐群,张淑芬. 金属有机骨架材料修饰玻碳电极循环伏安法测定维生素C片中抗坏血酸[J]. 理化检验－化学分册, 2017, 53(11): 1259～1264
共有人对该论文发表了看法，其中：
人认为该论文很差
人认为该论文较差
人认为该论文一般
人认为该论文较好
人认为该论文很好
参考文献
【1】SOLATIE D, CARBOL P, BETTI M, et al. Ion chromatography inductively coupled plasma mass spectrometry (IC-ICP-MS) and radiometric techniques for the determination of actinides in aqueous leachate solutions from uranium oxide[J]. Fresenius Journal of Analytical Chemistry, 2003,68(1):88-94.
【2】曾翔云.维生素C的生理功能与膳食保障[J].中国食物与营养, 2005(4):52-54.
【3】高志杰,李静涛,饶小思,等.高效液相色谱-二极管阵列检测器法检测饮料中Vc的研究[J].中国卫生检验杂志, 2006,16(4):446-447.
【4】邵丽华.饮料中还原型维生素C与总维生素C测定方法的研究[J].营养学报, 2007,29(2):192-194.
【5】王爱月,张向兵,李发生,等.高效液相色谱法测定食品及保健品中维生素C含量的研究[J].中国卫生检验杂志, 2006,16(10):1175-1176.
【6】毕玉琦,田甜,凌云.GB 14881-2013《食品生产通用卫生规范》解读[J].标准科学, 2014(4):65-68.
【7】WANG S F, DAN D. Differential pulse voltammetry determination of ascorbic acid with ferrocene-L-cysteine self-assembled supramolecular film modified electrode[J]. Sensors and Actuators B Chemical, 2004,97(2):373-378.
【8】刘国如,刘永锁,陈振玲,等.高效液相色谱法测定维生素C注射液含量[J].中国医药导报, 2011,27(8):50-51.
【9】TANG Y J, WU M J. A quick method for the simultaneous determination of ascorbic acid and sorbic acid in fruit juices by capillary zone electrophoresis[J]. Talanta, 2005,65(3):794-798.
【10】解文秀,马玉翔.铁(Ⅱ)-邻菲罗啉-桑色素体系分光光度法测定果蔬中的维生素C[J].山东教育学院学报, 2002,17(4):47-48.
【11】谭学才,韦冬萍,邓光辉,等.维生素C在多壁碳纳米管/壳聚糖复合膜修饰玻碳电极上的电化学行为及测定[J].分析测试学报, 2007,26(5):662-666.
【12】LI B H, YU T H, WENG C Y, et al. Thermal and plasma synthesis of metal oxide nanoparticles from MOFs with SERS characterization[J]. Vibrational Spectroscopy, 2016,84:146-152.
【13】CHIZALLET C, LAZARE S, BAZER-BACHI D, et al. Catalysis of transesterification by a nonfunctionalized metal organic framework:Acido-basicity at the external surface of ZIF-8 probed by FTIR and ab initio calculations[J]. Journal of the American Chemical Society, 2010,132(35):12365-12377.
【2】曾翔云.维生素C的生理功能与膳食保障[J].中国食物与营养, 2005(4):52-54.
【3】高志杰,李静涛,饶小思,等.高效液相色谱-二极管阵列检测器法检测饮料中Vc的研究[J].中国卫生检验杂志, 2006,16(4):446-447.
【4】邵丽华.饮料中还原型维生素C与总维生素C测定方法的研究[J].营养学报, 2007,29(2):192-194.
【5】王爱月,张向兵,李发生,等.高效液相色谱法测定食品及保健品中维生素C含量的研究[J].中国卫生检验杂志, 2006,16(10):1175-1176.
【6】毕玉琦,田甜,凌云.GB 14881-2013《食品生产通用卫生规范》解读[J].标准科学, 2014(4):65-68.
【7】WANG S F, DAN D. Differential pulse voltammetry determination of ascorbic acid with ferrocene-L-cysteine self-assembled supramolecular film modified electrode[J]. Sensors and Actuators B Chemical, 2004,97(2):373-378.
【8】刘国如,刘永锁,陈振玲,等.高效液相色谱法测定维生素C注射液含量[J].中国医药导报, 2011,27(8):50-51.
【9】TANG Y J, WU M J. A quick method for the simultaneous determination of ascorbic acid and sorbic acid in fruit juices by capillary zone electrophoresis[J]. Talanta, 2005,65(3):794-798.
【10】解文秀,马玉翔.铁(Ⅱ)-邻菲罗啉-桑色素体系分光光度法测定果蔬中的维生素C[J].山东教育学院学报, 2002,17(4):47-48.
【11】谭学才,韦冬萍,邓光辉,等.维生素C在多壁碳纳米管/壳聚糖复合膜修饰玻碳电极上的电化学行为及测定[J].分析测试学报, 2007,26(5):662-666.
【12】LI B H, YU T H, WENG C Y, et al. Thermal and plasma synthesis of metal oxide nanoparticles from MOFs with SERS characterization[J]. Vibrational Spectroscopy, 2016,84:146-152.
【13】CHIZALLET C, LAZARE S, BAZER-BACHI D, et al. Catalysis of transesterification by a nonfunctionalized metal organic framework:Acido-basicity at the external surface of ZIF-8 probed by FTIR and ab initio calculations[J]. Journal of the American Chemical Society, 2010,132(35):12365-12377.
相关信息
