提出了高效液相色谱法测定PM_2.5样品中多溴二苯醚（PBDEs）含量的方法。采集后的样品以二氯甲烷-正己烷（3+1）混合液为萃取剂采用快速溶剂萃取法进行萃取。萃取液经净化、过滤后，以C₁₈色谱柱为固定相，以甲醇-磷酸盐缓冲溶液（93+7）混合液为流动相进行高效液相色谱分离测定。PBDEs的质量浓度在10.00~250.00 μg·L^-1内与其峰面积呈线性关系，检出限（3σ/s）为1.01~5.34 μg·L^-1。按上述方法对上海市浦东新区和青浦区的PM_2.5样品中PBDEs进行测定，并简述了多溴二苯醚同系物含量分布和随季节分布。

A high performance liquid chromatographic (HPLC) method was proposed for determination of polybrominated diphenyl ethers(PBDEs) in PM_2.5 samples. The collected samples were extracted by accelerated solvent extraction (ASE) with dichloromethane-hexane (3+1) mixture as the extractant. After purification and filtration, the solution was separated and PBDEs in the solution were determined by HPLC with C₁₈ column as stationary phase and methanol-phosphate buffer solution (93+7) as mobile phase. Linear relationships between values of peak area and mass concentration of PBDEs were found in the range of 10.00-250.00 μg·L^-1, with detection limits (3σ/s) in the range of 1.01-5.34 μg·L^-1. PBDEs in PM_2.5 samples in Pudong New district and Qingpu district of Shanghai city were analyzed by the above method, and content distribution and seasonal distribution of the homologs of PBDEs were briefly described.