采用超高效液相色谱-质谱法测定醋五味子中五味子酯甲、五味子酚、五味子甲素、五味子乙素、五味子丙素、五味子醇甲和五味子醇乙等7种木脂素的含量。醋五味子样品0.200 0 g用甲醇10 mL超声提取30 min。以ACQUITY UPLC BEH C₁₈色谱柱为分离柱，以不同体积比的乙腈和0.1%（体积分数）甲酸溶液的混合液为流动相进行梯度洗脱，质谱分析中采用电喷雾正离子源和选择离子监测模式。7种木脂素的质量浓度在一定范围内与其对应的峰面积呈线性关系，方法的检出限（3S/N）为0.001~0.050 mg·L^-1。对6.0 mg·L^-1的7种木脂素混合标准溶液连续测定6次，测定值的相对标准偏差为1.2%~3.5%。方法用于醋五味子样品的分析，加标回收率为85.4%~99.3%。

UHPLC-MS was applied to the determination of 7 lignans, i.e. Schisantherrin A, Schisanhenol, Deoxyschisandrin, Schisandrin B, Schisandrin C, Schisandrin and Schisandrol B in Schisandra vinegar products. The sample (0.200 0 g) was extracted ultrasonically with methanol (10 mL) for 30 min. ACQUITY UPLC BEH C₁₈ chromatographic column was used as stationary phase, and the mixture of acetonitrile and 0.1% (φ) formic acid solution mixed in different ratios was used as mobile phase in gradient elution. ESI⁺ and the selected ion monitoring mode were adopted in MS. Linear relationships between values of peak area and mass concentration of the 7 lignans were kept in definite ranges. Detection limits (3S/N) of the method ranged from 0.001 to 0.050 mg·L^-1. Precision of the method was tested at the concentration level of 6.0 mg·L^-1 of the 7 lignans mixed standard solution for 6 determinations, values of RSDs found were in the range of 1.2%-3.5%. The proposed method was applied to the analysis of samples of Schisandra vinegar products, giving values of recovery in the range of 85.4%-99.3%.