采用高效液相色谱联用电感耦合等离子体质谱法（ICP-MS）测定畜肉制品中的一甲基砷、二甲基砷、三价砷、五价砷、砷甜菜碱和砷胆碱。称取经组织粉碎机粉碎的样品约3.0 g置于不锈钢萃取池中，加入6 g石英砂，搅拌均匀，以甲醇（2+1）溶液为提取溶剂，进行加速溶剂萃取。提取完成后，将提取液用甲醇（2+1）溶液定容至100 mL，经0.45 μm滤膜过滤。采用Dionex IonPac AS-17色谱柱（250 mm×4.0 mm，10 μm）分离滤液中的6种砷形态，以20 mmol·L^-1 NH₄HCO₃溶液为流动相在1.0 mL·min^-1流量下进行洗脱，采用ICP-MS测定洗脱液中6种砷形态。结果表明：6种砷形态质量浓度均在0.5~50.0 μg·L^-1内与对应的响应强度呈线性关系，检出限（3S/N）在0.15~0.24 μg·kg^-1之间。加标回收率在86.0%~108%之间，测定值的相对标准偏差（n=6）在2.6%~3.9%之间。

A method of HPLC-ICP-MS was applied to the determination of methyl arsenic, dimethyl arsenic, arsenic(Ⅲ), arsenic(Ⅴ), arsenic choline and arsenic betaine in livestock products. About 3.0 g of the sample pulverized by a tissue pulverizer was added into a stainless steel extraction tank, and 6 g of quartz sand was added. The mixture was stirred uniformly, and methanol (2+1) solution was used as extraction solvent to carry out accelerated solvent extraction. After the extraction was completed, the extract was made up to 100 mL with methanol (2+1) solution, and filtered through a 0.45 μm filter membrane. The 6 arsenic species were seperated on a Dionex IonPac AS-17 column (250 mm×4.0 mm, 10 μm), with 20 mmol·L^-1 NH₄HCO₃ solution as mobile phase for elution at a flow rate of 1.0 mL·min^-1. ICP-MS was used to determine the 6 arsenic species in the eluate. The result showed that linear relationships were found between response intensity and mass concentration of the 6 arsenic species in the same range of 0.5-50.0 μg·L^-1, with detection limits (3S/N) in the range 0.15-0.24 μg·kg^-1. Values of recovery obtained by standard addition method were in the range of 86.0%-108%, and RSDs (n=6) were in the range of 2.6%-3.9%.