水产品中全氟化合物的分析方法和分布特征的研究进展
Research Progress on Analytical Methods and Distribution Characteristics of Perfluorinated Compounds in Aquatic Products
摘 要
综述了不同水产品（无脊椎动物、贝类、鱼类、海鸟、哺乳动物等）样品中全氟化合物（PFCs）的提取方法（有机溶剂-水提取、碱性消化提取、离子对液液提取、加压液体萃取以及超声萃取）、净化方法（二氧化硅柱层析、分散石墨化碳和/或弱阴离子交换固相萃取、混合模式固相萃取；QuEChERS或分散固相萃取；反向液液萃取；凝胶渗透色谱；低温冷冻去脂）、测定方法[超高效液相色谱-串联质谱法（UPLC-MS/MS）、湍流色谱-串联质谱法（TFC-MS/MS）、纳升液相色谱-串联质谱法（nano LC-MS/MS）、超高效液相色谱-飞行时间-质谱法（UPLC-TOF-MS）]和分布物征的研究进展，并对其进行了展望（引用文献76篇）。
水产品
前处理方法
测定方法
分布特征
综述
perfluorinated compound
pretreatment method
determination method
distribution characteristic
review
Abstract
Research progress of extracting methods (organic solvent-water extraction, alkaline digestion extraction, ion-pair liquid-liquid extraction, pressurized liquid extraction and ultrasonic extraction), purification methods (silica column chromatography, dispersed graphitized carbon and/or weak anion exchange solid phase extraction, mixed mode solid phase extraction, QuEChERS or dispersed solid phase extraction, reverse liquid-liquid extraction, gel permeation chromatography, low-temperature freezing degreasing), determination methods (UPLC-MS/MS, TFC-MS/MS, nano LC-MS/MS, UPLC-TOF-MS) and distribution characteristics of the perfluorinated compounds in samples of different aquatic products (invertebrates, shellfish, fish, seabirds mammals, etc) were reviewed, and prospects was made for it (76 references cited).
中图分类号 O65 DOI 10.11973/lhjy-hx202006021
所属栏目 综述
基金项目 浙江省自然科学基金项目（LY17C200009）；浙江省科技项目（2017F10018）
收稿日期 2019/9/3
修改稿日期
网络出版日期
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备注李佩佩,工程师,硕士,主要从事水产品质量安全的研究工作
引用该论文: LI Peipei,LONG Ju,FANG Yi,YAN Zhongyong,ZHANG Xiaojun. Research Progress on Analytical Methods and Distribution Characteristics of Perfluorinated Compounds in Aquatic Products[J]. Physical Testing and Chemical Analysis part B:Chemical Analysis, 2020, 56(6): 735～744
李佩佩,龙举,方益,严忠雍,张小军. 水产品中全氟化合物的分析方法和分布特征的研究进展[J]. 理化检验－化学分册, 2020, 56(6): 735～744
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参考文献
【1】GIESY J P, KANNAN K. Peer reviewed:Perfluorochemical surfactants in the environment[J]. Environmental Science and Technology, 2002,36(7):146-152.
【2】PREVEDOUROS K, COUSINS I T, BUCK R C, et al. Sources, fate and transport of perfluorocarboxylates[J]. Environmental Science and Technology, 2006,40(1):32-44.
【3】NAILE J E, KHIM J S, HONG S, et al. Distributions and bioconcentration characteristics of perfluorinated compounds in environmental samples collected from the west Coast of Korea[J]. Chemosphere, 2013,90(2):387-394.
【4】LAM N H, CHO C R, LEE J S, et al. Perfluorinated alkyl substances in water, sediment, plankton and fish from Korean Rivers and lakes:A nationwide survey[J]. Science of the Total Environment, 2014,491/492:154-162.
【5】ZHAO Z, TANG J H, MI L J, et al. Perfluoroalkyl and polyfluoroalkyl substances in the lower atmosphere and surface waters of the Chinese Bohai Sea, Yellow Sea, and Yangtze River estuary[J]. Science of the Total Environment, 2017,599/600:114-123.
【6】AHRENS L, SHOEIB M, DEL VENTO S, et al. Polyfluoroalkyl compounds in the Canadian Arctic atmosphere[J]. Environmental Chemistry, 2011,8(4):399-406.
【7】AHRENS L, NORSTRÖM K, VIKTOR T, et al. Stockholm Arlanda Airport as a source of per- and polyfluoroalkyl substances to water,sediment and fish[J]. Chemosphere, 2015,129:33-38.
【8】ZHU Z Y, WANG T Y, WANG P, et al. Perfluoroalkyl and polyfluoroalkyl substances in sediments from South Bohai coastal watersheds, China[J]. Marine Pollution Bulletin, 2014,85(2):619-627.
【9】FAIR P A, WOLF B, WHITE N D, et al. Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, South Carolina, United States:Exposure and risk assessment[J]. Environmental Research, 2019,171:266-277.
【10】PÉREZ F, LLORCA M, KÖCK-SCHULMEYER M, et al. Assessment of perfluoroalkyl substances in food items at global scale[J]. Environmental Research, 2014,135:181-189.
【11】CHO C R, LAM N H, CHO B M, et al. Concentration and correlations of perfluoroalkyl substances in whole blood among subjects from three different geographical areas in Korea[J]. Science of the Total Environment, 2015,512/513:397-405.
【12】MORA A M, OKEN E, RIFAS-SHIMAN S L, et al. Prenatal exposure to perfluoroalkyl substances and adiposity in early and mid-childhood[J]. Environmental Health Perspectives, 2017,125(3):467-473.
【13】GONZÁLEZ-GAYA B, DACHS J, ROSCALES J L, et al. Perfluoroalkylated substances in the global tropical and subtropical surface oceans[J]. Environmental Science and Technology, 2014,48(22):13076-13084.
【14】CASAL P, GONZÁLEZ-GAYA B, ZHANG Y F, et al. Accumulation of perfluoroalkylated substances in oceanic plankton[J]. Environmental Science and Technology, 2017,51(5):2766-2775.
【15】CHANG E T, ADAMI H O, BOFFETTA P, et al. A critical review of perfluorooctanoate and perfluorooctane sulfonate exposure and cancer risk in humans[J]. Critical Reviews in Toxicology, 2014,44(S1):1-81.
【16】HUMBLET O, DIAZ-RAMIREZ L G, BALMES J R, et al. Perfluoroalkyl chemicals and asthma among children 12-19 years of age:NHANES (1999-2008)[J]. Environmental Health Perspectives, 2014,122(10):1129-1133.
【17】SIMPSON C, WINQUIST A, LALLY C, et al. Relation between perfluorooctanoic acid exposure and strokes in a large cohort living near a chemical plant[J]. Environmental Research, 2013,127:22-28.
【18】GEBBINK W A, GLYNN A, DARNERUD P O, et al. Perfluoroalkyl acids and their precursors in Swedish food:The relative importance of direct and indirect dietary exposure[J]. Environmental Pollution, 2015,198:108-115.
【19】ZABALETA I, BIZKARGUENAGA E, PRIETO A, et al. Simultaneous determination of perfluorinated compounds and their potential precursors in mussel tissue and fish muscle tissue and liver samples by liquid chromatography-electrospray-tandem mass spectrometry[J]. Journal of Chromatography A, 2015,1387:13-23.
【20】GAO Y, LI X M, LI X Q, et al. Simultaneous determination of 21 trace perfluoroalkyl substances in fish by isotope dilution ultrahigh performance liquid chromatography tandem mass spectrometry[J]. Journal of Chromatography B, 2018,1084:45-52.
【21】DELINSKY A D, STRYNAR M J, NAKAYAMA S F, et al. Determination of ten perfluorinated compounds in bluegill sunfish (Lepomis macrochirus) fillets[J]. Environmental Research, 2009,109(8):975-984.
【22】SHI Y L, VESTERGREN R, NOST T H, et al. Probing the differential tissue distribution and bioaccumulation behavior of per- and polyfluoroalkyl substances of varying chain-lengths, isomeric structures and functional groups in crucian carp[J]. Environmental Science and Technology, 2018,52(8):4592-4600.
【23】CUI Q Q, PAN Y T, ZHANG H X, et al. Occurrence and tissue distribution of novel perfluoroether carboxylic and sulfonic acids and legacy per/polyfluoroalkyl substances in black-spotted frog (pelophylax nigromaculatus)[J]. Environmental Science and Technology, 2018,52(3):982-990.
【24】MARTIN J W, SMITHWICK M M, BRAUNE B M, et al. Identification of long-chain perfluorinated acids in biota from the Canadian arctic[J]. Environmental Science and Technology, 2004,38(2):373-380.
【25】STOCK N L, FURDUI V I, MUIR D C G, et al. Perfluoroalkyl contaminants in the Canadian arctic:evidence of atmospheric transport and local contamination[J]. Environmental Science and Technology, 2007,41(10):3529-3536.
【26】LLORCA M, FARRÉ M, PICÓ Y, et al. Development and validation of a pressurized liquid extraction liquid chromatography-tandem mass spectrometry method for perfluorinated compounds determination in fish[J]. Journal of Chromatography A, 2009,1216(43):7195-7204.
【27】ULLAH S, HUBER S, BIGNERT A, et al. Temporal trends of perfluoroalkane sulfonic acids and their sulfonamide-based precursors in herring from the Swedish west Coast 1991-2011 including isomer-specific considerations[J]. Environment International, 2014,65:63-72.
【28】ZABALETA I, BIZKARGUENAGA E, IPARRAGIRRE A, et al. Focused ultrasound solid-liquid extraction for the determination of perfluorinated compounds in fish, vegetables and amended soil[J]. Journal of Chromatography A, 2014,1331:27-37.
【29】TITTLEMIER S A, PEPPER K, EDWARDS L, et al. Development and characterization of a solvent extraction-gas chromatographic/mass spectrometric method for the analysis of perfluorooctanesulfonamide compounds in solid matrices[J]. Journal of Chromatography A, 2005,1066(1/2):189-195.
【30】LAW R J, BERSUDER P, MEAD L K, et al. PFOS and PFOA in the livers of harbour porpoises (Phocoena phocoena) stranded or bycaught around the UK[J]. Marine Pollution Bulletin, 2008,56(4):792-797.
【31】KÄRRMAN A, DOMINGO J L, LLEBARIA X, et al. Biomonitoring perfluorinated compounds in Catalonia,Spain:concentrations and trends in human liver and milk samples[J]. Environmental Science and Pollution Research, 2010,17(3):750-758.
【32】RUBARTH J, DREYER A, GUSE N, et al. Perfluorinated compounds in red-throated divers from the German Baltic Sea:new findings from their distribution in 10 different tissues[J]. Environmental Chemistry, 2011,8(4):419-428.
【33】GUO M M, ZHENG G C, PENG J X, et al. Distribution of perfluorinated alkyl substances in marine shellfish along the Chinese Bohai Sea Coast[J]. Journal of Environmental Science and Health, Part B, 2019,54(4):271-280.
【34】郭萌萌,吴海燕,李兆新,等.超快速液相色谱-串联质谱法检测水产品中23种全氟烷基化合物[J].分析化学, 2013,41(9):1322-1327.
【35】LACINA O, HRADKOVA P, PULKRABOVA J, et al. Simple,high throughput ultra-high performance liquid chromatography/tandem mass spectrometry trace analysis of perfluorinated alkylated substances in food of animal origin:Milk and fish[J]. Journal of Chromatography A, 2011,1218(28):4312-4321.
【36】TANG C M, TAN J H, WANG C W, et al. Determination of perfluorooctanoic acid and perfluorooctane sulfonate in cooking oil and pig adipose tissue using reversed-phase liquid-liquid extraction followed by high performance liquid chromatography tandem mass spectrometry[J]. Journal of Chromatography A, 2014,1341:50-56.
【37】YANG L L, JIN F, ZHANG P, et al. Simultaneous determination of perfluorinated compounds in edible oil by gel-permeation chromatography combined with dispersive solid-phase extraction and liquid chromatography-tandem mass spectrometry[J]. Journal of Agricultural and Food Chemistry, 2015,63(38):8364-8371.
【38】VAN LEEUWEN S P J, SWART C P, VAN DER VEEN I, et al. Significant improvements in the analysis of perfluorinated compounds in water and fish:Results from an interlaboratory method evaluation study[J]. Journal of Chromatography A, 2009,1216(3):401-409.
【39】LORENZO M, CAMPO J, PICÓ Y. Analytical challenges to determine emerging persistent organic pollutants in aquatic ecosystems[J]. TrAC Trends in Analytical Chemistry, 2018,103:137-155.
【40】MAZZONI M, POLESELLO S, RUSCONI M, et al. Liquid chromatography mass spectrometry determination of perfluoroalkyl acids in environmental solid extracts after phospholipid removal and on-line turbulent flow chromatography purification[J]. Journal of Chromatography A, 2016,1453:62-70.
【41】郭萌萌,国佼,吴海燕,等.通过式固相萃取-液相色谱-四极杆/静电场轨道阱高分辨质谱快速筛查鱼肉中全氟化合物及其前体物质[J].分析化学, 2016,44(10):1504-1513.
【42】ZACS D, BARTKEVICS V. Trace determination of perfluorooctane sulfonate and perfluorooctanoic acid in environmental samples (surface water, wastewater, biota, sediments, and sewage sludge) using liquid chromatography-Orbitrap mass spectrometry[J]. Journal of Chromatography A, 2016,1473:109-121.
【43】SZOSTEK B, PRICKETT K B. Determination of 8:2 fluorotelomer alcohol in animal plasma and tissues by gas chromatography-mass spectrometry[J]. Journal of Chromatography B, 2004,813(1/2):313-321.
【44】CHEN H, HAN J B, CHENG J Y, et al. Distribution, bioaccumulation and trophic transfer of chlorinated polyfluoroalkyl ether sulfonic acids in the marine food web of Bohai, China[J]. Environmental Pollution, 2018,241:504-510.
【45】CERVENY D, GRABIC R, FEDOROVA G, et al. Perfluoroalkyl substances in aquatic environment-comparison of fish and passive sampling approaches[J]. Environmental Research, 2016,144:92-98.
【46】COUDERC M, POIRIER L, ZALOUK-VERGNOUX A, et al. Occurrence of POPs and other persistent organic contaminants in the European eel (Anguilla Anguilla) from the Loire estuary,France[J]. Science of the Total Environment, 2015,505:199-215.
【47】CAMPO J, LORENZO M, PÉREZ F, et al. Analysis of the presence of perfluoroalkyl substances in water, sediment and biota of the Jucar River (E Spain). Sources, partitioning and relationships with water physical characteristics[J]. Environmental Research, 2016,147:503-512.
【48】BERLIOZ-BARBIER A, BULETÉ A, FABURÉ J, et al. Multi-residue analysis of emerging pollutants in benthic invertebrates by modified micro-quick-easy-cheap-efficient-rugged-safe extraction and nanoliquid chromatography-nanospray-tandem mass spectrometry analysis[J]. Journal of Chromatography A, 2014,1367:16-32.
【49】VILLAVERDE-DE-SÁA E, QUINTANA J B, RODIL R, et al. Determination of perfluorinated compounds in mollusks by matrix solid-phase dispersion and liquid chromatography-tandem mass spectrometry[J]. Analytical and Bioanalytical Chemistry, 2012,402(1):509-518.
【50】PICÓ Y, FARRÉ M, BARCELÓ D. Quantitative profiling of perfluoroalkyl substances by ultrahigh-performance liquid chromatography and hybrid quadrupole time-of-flight mass spectrometry[J]. Analytical and Bioanalytical Chemistry, 2015,407(15):4247-4259.
【51】MARTÍN J, ZAFRA-GÓMEZ A, HIDALGO F, et al. Multi-residue analysis of 36 priority and emerging pollutants in marine echinoderms (Holothuria tubulosa) and marine sediments by solid-liquid extraction followed by dispersive solid phase extraction and liquid chromatography-tandem mass spectrometry analysis[J]. Talanta, 2017,166:336-348.
【52】BOSSI R, DAM M, RIGÉT F F. Perfluorinated alkyl substances (PFAS) in terrestrial environments in Greenland and Faroe Islands[J]. Chemosphere, 2015,129:164-169.
【53】BUTT C M, BERGER U, BOSSI R, et al. Levels and trends of poly- and perfluorinated compounds in the arctic environment[J]. Science of the Total Environment, 2010,408(15):2936-2965.
【54】WILD S, MCLAGAN D, SCHLABACH M, et al. An Antarctic research station as a source of brominated and perfluorinated persistent organic pollutants to the local environment[J]. Environmental Science and Technology, 2015,49(1):103-112.
【55】VESTERGREN R, COUSINS I T. Tracking the pathways of human exposure to perfluorocarboxylates[J]. Environmental Science and Technology, 2009,43(15):5565-5575.
【56】BERGER U, GLYNN A, HOLMSTRÖM K E, et al. Fish consumption as a source of human exposure to perfluorinated alkyl substances in Sweden-Analysis of edible fish from Lake V ttern and the Baltic Sea[J]. Chemosphere, 2009,76(6):799-804.
【57】ZHOU Z, SHI Y L, VESTERGREN R, et al. Highly elevated serum concentrations of perfluoroalkyl substances in fishery employees from Tangxun lake, China[J]. Environmental Science and Technology, 2014,48(7):3864-3874.
【58】BJERMO H, DARNERUD P O, PEARSON M, et al. Serum concentrations of perfluorinated alkyl acids and their associations with diet and personal characteristics among Swedish adults[J]. Molecular Nutrition and Food Research, 2013,57(12):2206-2215.
【59】DALLAIRE R, AYOTTE P, PEREG D, et al. Determinants of plasma concentrations of perfluorooctanesulfonate and brominated organic compounds in nunavik Inuit adults (Canada)[J]. Environmental Science and Technology, 2009,43(13):5130-5136.
【60】HAUG L S, THOMSEN C, BRANTSÆTER A L, et al. Diet and particularly seafood are major sources of perfluorinated compounds in humans[J]. Environment International, 2010,36(7):772-778.
【61】PAN C G, ZHAO J L, LIU Y S, et al. Bioaccumulation and risk assessment of per- and polyfluoroalkyl substances in wild freshwater fish from Rivers in the Pearl River Delta region,South China[J]. Ecotoxicology and Environmental Safety, 2014,107:192-199.
【62】MARTIN J W, MABURY S A, SOLOMON K R, et al. Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (oncorhynchus mykiss)[J]. Environmental Toxicology and Chemistry, 2003,22(1):196-196.
【63】BECKER A M, GERSTMANN S, FRANK H. Perfluorooctanoic acid and perfluorooctane sulfonate in two fish species collected from the roter main river, Bayreuth, Germany[J]. Bulletin of Environmental Contamination and Toxicology, 2010,84(1):132-135.
【64】SHI Y L, WANG J M, PAN Y Y, et al. Tissue distribution of perfluorinated compounds in farmed freshwater fish and human exposure by consumption[J]. Environmental Toxicology and Chemistry, 2012,31(4):717-723.
【65】胡哲.不同生物介质中全氟化合物的分布特征及富集规律研究[D].武汉:华中农业大学, 2016.
【66】国佼,郭萌萌,吴海燕,等.双固相萃取柱净化-超快速液相色谱-串联质谱法同时测定贝类组织中全氟羧酸及其前体物质[J].食品科学, 2017,38(20):248-255.
【67】WU Y N, WANG Y X, LI J G, et al. Perfluorinated compounds in seafood from coastal areas in China[J]. Environment International, 2012,42:67-71.
【68】ZHAO Y G, WAN H T, LAW A Y S, et al. Risk assessment for human consumption of perfluorinated compound-contaminated freshwater and marine fish from Hong Kong and Xiamen[J]. Chemosphere, 2011,85(2):277-283.
【69】CLARKE D B, BAILEY V A, ROUTLEDGE A, et al. Dietary intake estimate for perfluorooctanesulphonic acid (PFOS) and other perfluorocompounds (PFCs) in UK retail foods following determination using standard addition LC-MS/MS[J]. Food Additives and Contaminants:Part A, 2010,27(4):530-545.
【70】DEL GOBBO L, TITTLEMIER S, DIAMOND M, et al. Cooking decreases observed perfluorinated compound concentrations in fish[J]. Journal of Agricultural and Food Chemistry, 2008,56(16):7551-7559.
【71】BHAVSAR S P, ZHANG X M, GUO R, et al. Cooking fish is not effective in reducing exposure to perfluoroalkyl and polyfluoroalkyl substances[J]. Environment International, 2014,66:107-114.
【72】VASSILIADOU I, COSTOPOULOU D, KALOGEROPOULOS N, et al. Levels of perfluorinated compounds in raw and cooked Mediterranean finfish and shellfish[J]. Chemosphere, 2015,127:117-126.
【73】JEONG Y J, BANG S, KIM J, et al. Comparing levels of perfluorinated compounds in processed marine products[J]. Food and Chemical Toxicology, 2019,126:199-210.
【74】MUNOZ G, BUDZINSKI H, BABUT M, et al. Evidence for the trophic transfer of perfluoroalkylated substances in a temperate macrotidal estuary[J]. Environmental Science and Technology, 2017,51(15):8450-8459.
【75】韩同竹.胶州湾海水和生物体中全氟化合物的分布特征及来源解析[D].青岛:国家海洋局第一海洋研究所, 2018.
【2】PREVEDOUROS K, COUSINS I T, BUCK R C, et al. Sources, fate and transport of perfluorocarboxylates[J]. Environmental Science and Technology, 2006,40(1):32-44.
【3】NAILE J E, KHIM J S, HONG S, et al. Distributions and bioconcentration characteristics of perfluorinated compounds in environmental samples collected from the west Coast of Korea[J]. Chemosphere, 2013,90(2):387-394.
【4】LAM N H, CHO C R, LEE J S, et al. Perfluorinated alkyl substances in water, sediment, plankton and fish from Korean Rivers and lakes:A nationwide survey[J]. Science of the Total Environment, 2014,491/492:154-162.
【5】ZHAO Z, TANG J H, MI L J, et al. Perfluoroalkyl and polyfluoroalkyl substances in the lower atmosphere and surface waters of the Chinese Bohai Sea, Yellow Sea, and Yangtze River estuary[J]. Science of the Total Environment, 2017,599/600:114-123.
【6】AHRENS L, SHOEIB M, DEL VENTO S, et al. Polyfluoroalkyl compounds in the Canadian Arctic atmosphere[J]. Environmental Chemistry, 2011,8(4):399-406.
【7】AHRENS L, NORSTRÖM K, VIKTOR T, et al. Stockholm Arlanda Airport as a source of per- and polyfluoroalkyl substances to water,sediment and fish[J]. Chemosphere, 2015,129:33-38.
【8】ZHU Z Y, WANG T Y, WANG P, et al. Perfluoroalkyl and polyfluoroalkyl substances in sediments from South Bohai coastal watersheds, China[J]. Marine Pollution Bulletin, 2014,85(2):619-627.
【9】FAIR P A, WOLF B, WHITE N D, et al. Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, South Carolina, United States:Exposure and risk assessment[J]. Environmental Research, 2019,171:266-277.
【10】PÉREZ F, LLORCA M, KÖCK-SCHULMEYER M, et al. Assessment of perfluoroalkyl substances in food items at global scale[J]. Environmental Research, 2014,135:181-189.
【11】CHO C R, LAM N H, CHO B M, et al. Concentration and correlations of perfluoroalkyl substances in whole blood among subjects from three different geographical areas in Korea[J]. Science of the Total Environment, 2015,512/513:397-405.
【12】MORA A M, OKEN E, RIFAS-SHIMAN S L, et al. Prenatal exposure to perfluoroalkyl substances and adiposity in early and mid-childhood[J]. Environmental Health Perspectives, 2017,125(3):467-473.
【13】GONZÁLEZ-GAYA B, DACHS J, ROSCALES J L, et al. Perfluoroalkylated substances in the global tropical and subtropical surface oceans[J]. Environmental Science and Technology, 2014,48(22):13076-13084.
【14】CASAL P, GONZÁLEZ-GAYA B, ZHANG Y F, et al. Accumulation of perfluoroalkylated substances in oceanic plankton[J]. Environmental Science and Technology, 2017,51(5):2766-2775.
【15】CHANG E T, ADAMI H O, BOFFETTA P, et al. A critical review of perfluorooctanoate and perfluorooctane sulfonate exposure and cancer risk in humans[J]. Critical Reviews in Toxicology, 2014,44(S1):1-81.
【16】HUMBLET O, DIAZ-RAMIREZ L G, BALMES J R, et al. Perfluoroalkyl chemicals and asthma among children 12-19 years of age:NHANES (1999-2008)[J]. Environmental Health Perspectives, 2014,122(10):1129-1133.
【17】SIMPSON C, WINQUIST A, LALLY C, et al. Relation between perfluorooctanoic acid exposure and strokes in a large cohort living near a chemical plant[J]. Environmental Research, 2013,127:22-28.
【18】GEBBINK W A, GLYNN A, DARNERUD P O, et al. Perfluoroalkyl acids and their precursors in Swedish food:The relative importance of direct and indirect dietary exposure[J]. Environmental Pollution, 2015,198:108-115.
【19】ZABALETA I, BIZKARGUENAGA E, PRIETO A, et al. Simultaneous determination of perfluorinated compounds and their potential precursors in mussel tissue and fish muscle tissue and liver samples by liquid chromatography-electrospray-tandem mass spectrometry[J]. Journal of Chromatography A, 2015,1387:13-23.
【20】GAO Y, LI X M, LI X Q, et al. Simultaneous determination of 21 trace perfluoroalkyl substances in fish by isotope dilution ultrahigh performance liquid chromatography tandem mass spectrometry[J]. Journal of Chromatography B, 2018,1084:45-52.
【21】DELINSKY A D, STRYNAR M J, NAKAYAMA S F, et al. Determination of ten perfluorinated compounds in bluegill sunfish (Lepomis macrochirus) fillets[J]. Environmental Research, 2009,109(8):975-984.
【22】SHI Y L, VESTERGREN R, NOST T H, et al. Probing the differential tissue distribution and bioaccumulation behavior of per- and polyfluoroalkyl substances of varying chain-lengths, isomeric structures and functional groups in crucian carp[J]. Environmental Science and Technology, 2018,52(8):4592-4600.
【23】CUI Q Q, PAN Y T, ZHANG H X, et al. Occurrence and tissue distribution of novel perfluoroether carboxylic and sulfonic acids and legacy per/polyfluoroalkyl substances in black-spotted frog (pelophylax nigromaculatus)[J]. Environmental Science and Technology, 2018,52(3):982-990.
【24】MARTIN J W, SMITHWICK M M, BRAUNE B M, et al. Identification of long-chain perfluorinated acids in biota from the Canadian arctic[J]. Environmental Science and Technology, 2004,38(2):373-380.
【25】STOCK N L, FURDUI V I, MUIR D C G, et al. Perfluoroalkyl contaminants in the Canadian arctic:evidence of atmospheric transport and local contamination[J]. Environmental Science and Technology, 2007,41(10):3529-3536.
【26】LLORCA M, FARRÉ M, PICÓ Y, et al. Development and validation of a pressurized liquid extraction liquid chromatography-tandem mass spectrometry method for perfluorinated compounds determination in fish[J]. Journal of Chromatography A, 2009,1216(43):7195-7204.
【27】ULLAH S, HUBER S, BIGNERT A, et al. Temporal trends of perfluoroalkane sulfonic acids and their sulfonamide-based precursors in herring from the Swedish west Coast 1991-2011 including isomer-specific considerations[J]. Environment International, 2014,65:63-72.
【28】ZABALETA I, BIZKARGUENAGA E, IPARRAGIRRE A, et al. Focused ultrasound solid-liquid extraction for the determination of perfluorinated compounds in fish, vegetables and amended soil[J]. Journal of Chromatography A, 2014,1331:27-37.
【29】TITTLEMIER S A, PEPPER K, EDWARDS L, et al. Development and characterization of a solvent extraction-gas chromatographic/mass spectrometric method for the analysis of perfluorooctanesulfonamide compounds in solid matrices[J]. Journal of Chromatography A, 2005,1066(1/2):189-195.
【30】LAW R J, BERSUDER P, MEAD L K, et al. PFOS and PFOA in the livers of harbour porpoises (Phocoena phocoena) stranded or bycaught around the UK[J]. Marine Pollution Bulletin, 2008,56(4):792-797.
【31】KÄRRMAN A, DOMINGO J L, LLEBARIA X, et al. Biomonitoring perfluorinated compounds in Catalonia,Spain:concentrations and trends in human liver and milk samples[J]. Environmental Science and Pollution Research, 2010,17(3):750-758.
【32】RUBARTH J, DREYER A, GUSE N, et al. Perfluorinated compounds in red-throated divers from the German Baltic Sea:new findings from their distribution in 10 different tissues[J]. Environmental Chemistry, 2011,8(4):419-428.
【33】GUO M M, ZHENG G C, PENG J X, et al. Distribution of perfluorinated alkyl substances in marine shellfish along the Chinese Bohai Sea Coast[J]. Journal of Environmental Science and Health, Part B, 2019,54(4):271-280.
【34】郭萌萌,吴海燕,李兆新,等.超快速液相色谱-串联质谱法检测水产品中23种全氟烷基化合物[J].分析化学, 2013,41(9):1322-1327.
【35】LACINA O, HRADKOVA P, PULKRABOVA J, et al. Simple,high throughput ultra-high performance liquid chromatography/tandem mass spectrometry trace analysis of perfluorinated alkylated substances in food of animal origin:Milk and fish[J]. Journal of Chromatography A, 2011,1218(28):4312-4321.
【36】TANG C M, TAN J H, WANG C W, et al. Determination of perfluorooctanoic acid and perfluorooctane sulfonate in cooking oil and pig adipose tissue using reversed-phase liquid-liquid extraction followed by high performance liquid chromatography tandem mass spectrometry[J]. Journal of Chromatography A, 2014,1341:50-56.
【37】YANG L L, JIN F, ZHANG P, et al. Simultaneous determination of perfluorinated compounds in edible oil by gel-permeation chromatography combined with dispersive solid-phase extraction and liquid chromatography-tandem mass spectrometry[J]. Journal of Agricultural and Food Chemistry, 2015,63(38):8364-8371.
【38】VAN LEEUWEN S P J, SWART C P, VAN DER VEEN I, et al. Significant improvements in the analysis of perfluorinated compounds in water and fish:Results from an interlaboratory method evaluation study[J]. Journal of Chromatography A, 2009,1216(3):401-409.
【39】LORENZO M, CAMPO J, PICÓ Y. Analytical challenges to determine emerging persistent organic pollutants in aquatic ecosystems[J]. TrAC Trends in Analytical Chemistry, 2018,103:137-155.
【40】MAZZONI M, POLESELLO S, RUSCONI M, et al. Liquid chromatography mass spectrometry determination of perfluoroalkyl acids in environmental solid extracts after phospholipid removal and on-line turbulent flow chromatography purification[J]. Journal of Chromatography A, 2016,1453:62-70.
【41】郭萌萌,国佼,吴海燕,等.通过式固相萃取-液相色谱-四极杆/静电场轨道阱高分辨质谱快速筛查鱼肉中全氟化合物及其前体物质[J].分析化学, 2016,44(10):1504-1513.
【42】ZACS D, BARTKEVICS V. Trace determination of perfluorooctane sulfonate and perfluorooctanoic acid in environmental samples (surface water, wastewater, biota, sediments, and sewage sludge) using liquid chromatography-Orbitrap mass spectrometry[J]. Journal of Chromatography A, 2016,1473:109-121.
【43】SZOSTEK B, PRICKETT K B. Determination of 8:2 fluorotelomer alcohol in animal plasma and tissues by gas chromatography-mass spectrometry[J]. Journal of Chromatography B, 2004,813(1/2):313-321.
【44】CHEN H, HAN J B, CHENG J Y, et al. Distribution, bioaccumulation and trophic transfer of chlorinated polyfluoroalkyl ether sulfonic acids in the marine food web of Bohai, China[J]. Environmental Pollution, 2018,241:504-510.
【45】CERVENY D, GRABIC R, FEDOROVA G, et al. Perfluoroalkyl substances in aquatic environment-comparison of fish and passive sampling approaches[J]. Environmental Research, 2016,144:92-98.
【46】COUDERC M, POIRIER L, ZALOUK-VERGNOUX A, et al. Occurrence of POPs and other persistent organic contaminants in the European eel (Anguilla Anguilla) from the Loire estuary,France[J]. Science of the Total Environment, 2015,505:199-215.
【47】CAMPO J, LORENZO M, PÉREZ F, et al. Analysis of the presence of perfluoroalkyl substances in water, sediment and biota of the Jucar River (E Spain). Sources, partitioning and relationships with water physical characteristics[J]. Environmental Research, 2016,147:503-512.
【48】BERLIOZ-BARBIER A, BULETÉ A, FABURÉ J, et al. Multi-residue analysis of emerging pollutants in benthic invertebrates by modified micro-quick-easy-cheap-efficient-rugged-safe extraction and nanoliquid chromatography-nanospray-tandem mass spectrometry analysis[J]. Journal of Chromatography A, 2014,1367:16-32.
【49】VILLAVERDE-DE-SÁA E, QUINTANA J B, RODIL R, et al. Determination of perfluorinated compounds in mollusks by matrix solid-phase dispersion and liquid chromatography-tandem mass spectrometry[J]. Analytical and Bioanalytical Chemistry, 2012,402(1):509-518.
【50】PICÓ Y, FARRÉ M, BARCELÓ D. Quantitative profiling of perfluoroalkyl substances by ultrahigh-performance liquid chromatography and hybrid quadrupole time-of-flight mass spectrometry[J]. Analytical and Bioanalytical Chemistry, 2015,407(15):4247-4259.
【51】MARTÍN J, ZAFRA-GÓMEZ A, HIDALGO F, et al. Multi-residue analysis of 36 priority and emerging pollutants in marine echinoderms (Holothuria tubulosa) and marine sediments by solid-liquid extraction followed by dispersive solid phase extraction and liquid chromatography-tandem mass spectrometry analysis[J]. Talanta, 2017,166:336-348.
【52】BOSSI R, DAM M, RIGÉT F F. Perfluorinated alkyl substances (PFAS) in terrestrial environments in Greenland and Faroe Islands[J]. Chemosphere, 2015,129:164-169.
【53】BUTT C M, BERGER U, BOSSI R, et al. Levels and trends of poly- and perfluorinated compounds in the arctic environment[J]. Science of the Total Environment, 2010,408(15):2936-2965.
【54】WILD S, MCLAGAN D, SCHLABACH M, et al. An Antarctic research station as a source of brominated and perfluorinated persistent organic pollutants to the local environment[J]. Environmental Science and Technology, 2015,49(1):103-112.
【55】VESTERGREN R, COUSINS I T. Tracking the pathways of human exposure to perfluorocarboxylates[J]. Environmental Science and Technology, 2009,43(15):5565-5575.
【56】BERGER U, GLYNN A, HOLMSTRÖM K E, et al. Fish consumption as a source of human exposure to perfluorinated alkyl substances in Sweden-Analysis of edible fish from Lake V ttern and the Baltic Sea[J]. Chemosphere, 2009,76(6):799-804.
【57】ZHOU Z, SHI Y L, VESTERGREN R, et al. Highly elevated serum concentrations of perfluoroalkyl substances in fishery employees from Tangxun lake, China[J]. Environmental Science and Technology, 2014,48(7):3864-3874.
【58】BJERMO H, DARNERUD P O, PEARSON M, et al. Serum concentrations of perfluorinated alkyl acids and their associations with diet and personal characteristics among Swedish adults[J]. Molecular Nutrition and Food Research, 2013,57(12):2206-2215.
【59】DALLAIRE R, AYOTTE P, PEREG D, et al. Determinants of plasma concentrations of perfluorooctanesulfonate and brominated organic compounds in nunavik Inuit adults (Canada)[J]. Environmental Science and Technology, 2009,43(13):5130-5136.
【60】HAUG L S, THOMSEN C, BRANTSÆTER A L, et al. Diet and particularly seafood are major sources of perfluorinated compounds in humans[J]. Environment International, 2010,36(7):772-778.
【61】PAN C G, ZHAO J L, LIU Y S, et al. Bioaccumulation and risk assessment of per- and polyfluoroalkyl substances in wild freshwater fish from Rivers in the Pearl River Delta region,South China[J]. Ecotoxicology and Environmental Safety, 2014,107:192-199.
【62】MARTIN J W, MABURY S A, SOLOMON K R, et al. Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (oncorhynchus mykiss)[J]. Environmental Toxicology and Chemistry, 2003,22(1):196-196.
【63】BECKER A M, GERSTMANN S, FRANK H. Perfluorooctanoic acid and perfluorooctane sulfonate in two fish species collected from the roter main river, Bayreuth, Germany[J]. Bulletin of Environmental Contamination and Toxicology, 2010,84(1):132-135.
【64】SHI Y L, WANG J M, PAN Y Y, et al. Tissue distribution of perfluorinated compounds in farmed freshwater fish and human exposure by consumption[J]. Environmental Toxicology and Chemistry, 2012,31(4):717-723.
【65】胡哲.不同生物介质中全氟化合物的分布特征及富集规律研究[D].武汉:华中农业大学, 2016.
【66】国佼,郭萌萌,吴海燕,等.双固相萃取柱净化-超快速液相色谱-串联质谱法同时测定贝类组织中全氟羧酸及其前体物质[J].食品科学, 2017,38(20):248-255.
【67】WU Y N, WANG Y X, LI J G, et al. Perfluorinated compounds in seafood from coastal areas in China[J]. Environment International, 2012,42:67-71.
【68】ZHAO Y G, WAN H T, LAW A Y S, et al. Risk assessment for human consumption of perfluorinated compound-contaminated freshwater and marine fish from Hong Kong and Xiamen[J]. Chemosphere, 2011,85(2):277-283.
【69】CLARKE D B, BAILEY V A, ROUTLEDGE A, et al. Dietary intake estimate for perfluorooctanesulphonic acid (PFOS) and other perfluorocompounds (PFCs) in UK retail foods following determination using standard addition LC-MS/MS[J]. Food Additives and Contaminants:Part A, 2010,27(4):530-545.
【70】DEL GOBBO L, TITTLEMIER S, DIAMOND M, et al. Cooking decreases observed perfluorinated compound concentrations in fish[J]. Journal of Agricultural and Food Chemistry, 2008,56(16):7551-7559.
【71】BHAVSAR S P, ZHANG X M, GUO R, et al. Cooking fish is not effective in reducing exposure to perfluoroalkyl and polyfluoroalkyl substances[J]. Environment International, 2014,66:107-114.
【72】VASSILIADOU I, COSTOPOULOU D, KALOGEROPOULOS N, et al. Levels of perfluorinated compounds in raw and cooked Mediterranean finfish and shellfish[J]. Chemosphere, 2015,127:117-126.
【73】JEONG Y J, BANG S, KIM J, et al. Comparing levels of perfluorinated compounds in processed marine products[J]. Food and Chemical Toxicology, 2019,126:199-210.
【74】MUNOZ G, BUDZINSKI H, BABUT M, et al. Evidence for the trophic transfer of perfluoroalkylated substances in a temperate macrotidal estuary[J]. Environmental Science and Technology, 2017,51(15):8450-8459.
【75】韩同竹.胶州湾海水和生物体中全氟化合物的分布特征及来源解析[D].青岛:国家海洋局第一海洋研究所, 2018.
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