建立了超高效液相色谱法（UHPLC）测定食品接触材料聚对苯二甲酸乙二醇酯（PET）中的间苯二甲酸和对苯二甲酸特定迁移量的方法。按照以下参数进行迁移试验：①参考方法为国家标准GB 5009.156-2016和GB/T 23296.1-2009；②模拟液为4%（体积分数）乙酸溶液、10%（体积分数）乙醇溶液、20%（体积分数）乙醇溶液、50%（体积分数）乙醇溶液和橄榄油；③迁移温度为70℃，迁移时间为2 h。得到的迁移溶液供UHPLC进行分析，选择ShimSen-VD C₃₀色谱柱为固定相，以体积比为40：60的甲醇和7.5 mmol·L^-1磷酸二氢钾-磷酸缓冲溶液（pH 3.0）的混合溶液为流动相进行等度洗脱，在230 nm处用二极管阵列检测器（DAD）测定。以邻苯二甲酸为内标、用5种模拟液配制混合标准溶液系列，结果表明：对苯二甲酸、间苯二甲酸的线性范围为0.5~15.0 mg·L^-1，检出限（3S/N）为0.03~0.07 mg·L^-1。对实际样品进行3个浓度水平的加标回收试验，得到对苯二甲酸、间苯二甲酸的回收率为92.4%~106%，测定值的相对标准偏差（n=6）为0.17%~5.0%。用此方法分析了PET样品，未发现有这两种物质的迁移。

A method was developed for the simultaneous determination of migration amount of m-phthalic acid and p-phthalic acid in food contact material of ethylene terephthalate (PET) by ultra high performance liquid chromatography (UHPLC). Parameters for migration test were as follows:① national standards of GB 5009.156-2016 and GB/T 23296.1-2009 were adopted as reference methods; ② 4% (volume fraction) acetic acid solution, 10% (volume fraction) ethanol solution, 20% (volume fraction) ethanol solution, 50% (volume fraction) ethanol solution and olive oil were used as simulant solutions; ③ migration temperature was 70℃, and migration time was 2 h. The obtained migration solution was analyzed by UHPLC. ShimSen-VD C₃₀ chromatographic column was selected as the stationary phase. The mixture of methanol and 7.5 mmol·L^-1 potassium dihydrogen phosphate-phosphate buffer solution (pH 3.0) at volume ratio of 40:60 was used as the mobile phase for isocratic elution, and the content of p-phthalic acid and m-phthalic acid was determined with DAD at 230 nm. Using phthalate as the internal standard, a series of mixed standard solutions were prepared with above 5 simulant solutions. The results showed that linearity ranges of p-phthalic acid and m-phthalic acid was found within 0.5-15.0 mg·L^-1, with detection limits (3S/N) in the range of 0.03-0.07 mg·L^-1. The spiked recovery test was made on the actual sample at three concentration levels, giving results of p-phthalic acid and m-phthalic acid in the range of 92.4%-106%, and RSDs (n=6) of the determined values (n=6) ranged from 0.17% to 5.0%. The PET samples were analyzed by the proposed method, and no migration of these two substances was found.