采用物理吸附方法将溶菌酶固定在MCM-41介孔分子筛上，并与化学缓蚀剂[氨基三亚甲基膦酸（ATMP）与聚天冬氨酸（PASP）]复配用作循环冷却水缓蚀剂。利用电化学法分析复配缓蚀剂的缓蚀机理，并用失重法所测得的复配缓蚀剂缓蚀性能为指标优化复配条件。结果表明：复配缓蚀剂为混合型缓蚀剂，可以同时抑制腐蚀过程的阴极反应与阳极反应，最佳复配方案为固定化溶菌酶投加量0.7 g/L、ATMP质量浓度10 mg/L、PASP质量浓度20 mg/L，缓蚀率可达88.55%，循环冷却水对碳钢腐蚀速率降至0.017 3 mm/a，作用时间为11~13 d。

Lysozyme was immobilized on MCM-41 mesoporous molecular sieve by physical adsorption method, and then compounded with chemical inhibitors amino trimethylene phosphonic acid (ATMP) and sodium of polyaspartic acid (PASP) to act as the circulating cooling water inhibitor. Electrochemical methods were used to analyze the inhibition mechanism of the compound inhibitor, and the method of weight loss of was used to analyze the inhibition performance of the compound inhibitor which would be the index of the optimized compound condition. The results showed that the compound inhibitor was a mixed inhibitor, which could inhibit the cathodic reaction and the anodic reaction in the corrosion process at the same time. The optimal compound scheme was as follows, when the adding amount of immobilize lysozyme was 0.7 g/L, ATMP was 10 mg/L and PASP was 20 mg/L, the inhibition rate could be up to 88.55%, the corrosion rate of carbon steel in circulating cooling water would decrease to 0.0173 mm/a, and the action time could be up to 11-13 days.