对用电感耦合等离子体质谱法测定纯铁中21种元素（包括Li、Be、B、Al、Ti、Mn、Co、Ni、Cu、Zn等），通过加入高纯铁作为基体，试验考察了不同量的铁基体对上述被测元素的信号强度的影响。结果发现：铁基体质量浓度在40 mg·L^-1以内时，待测元素的相对信号强度与铁基体浓度保持较好的线性关系；当铁基体质量浓度增大至400 mg·L^-1时，除了Mn、Co两元素外，铁基体对其他待测元素均产生一定的抑制作用。基于对内标元素的基体效应分析，选择与待测元素有相似基体效应的内标元素，以校正基体效应。

In the ICP-MS determination of 21 elements (including Li, Be, B, Al, Ti, Mn, Co, Ni, Cu, Zn and etc.) in high purity iron, the matrix effect of iron at various concentration levels on MS signal intensities of the testing elements was studied. As shown by the results, when the mass concentrations of iron were within 40 mg·L^-1, values of relative signal intensities of the testing elements were found to keep linear relationships with the mass concentration of matrix iron, as the mass concentration of matrix iron was increased to 400 mg·L^-1, inhibitory action of iron on MS signal intensities of the testing elements, except Mn and Co, was observed. Through the matrix effect analysis of internal standard elements, the internal standard elements having similar matrix effect with the analyst elements were selected to correct the matrix effect.