白芷样品粉末（约2.5 g）用25 mL甲醇浸泡过夜后超声提取30 min，加入适量甲醇补足所失质量，提取液经0.22 μm有机膜过滤，采用超高效液相色谱法测定滤液中6种香豆素类成分的含量。以Waters ACQUITY UPLC BEH-C₁₈色谱柱为分离柱，用乙腈和水以不同比例混合的溶液为流动相进行梯度洗脱，用紫外检测器测定。6种香豆素类成分的质量浓度在一定范围内与其对应的峰面积呈线性关系，检出限（3S/N）为0.034~0.091 mg·L^-1。方法用于白芷样品的分析，加标回收率为93.2%~107%，测定值的相对标准偏差（n=6）为0.64%~1.7%。对9个不同产地的白芷样品中6种香豆素类成分的含量进行聚类分析和主成分分析，结果表明：聚类分析和主成分分析的结果一致，样品被分为3类。

The powder of angelicae dahurica sample (about 2.5 g) was immersed in 25 mL of methanol overnight, and then extracted ultrasonically for 30 min. Appropriate amount of methanol was added to make up for lost mass. The extract was filtered on 0.22 μm organic membrane. UHPLC was applied to the determination of 6 coumarin components in the filtrate. Waters ACQUITY UPLC BEH-C₁₈ chromatographic column was used as separation column, and the mixture of acetonitrile and water mixed in different ratios was used as mobile phase in gradient elution. UV detector was adopted in the determination. Linear relationships between values of peak area and mass concentration of the 6 coumarin components were kept in definite ranges, with detection limits (3S/N) in the range of 0.034-0.091 mg·L^-1. The proposed method was applied to the analysis of angelicae dahurica sample, giving values of recovery found by standard addition method and RSDs (n=6) of determined values in the ranges of 93.2%-107% and 0.64%-1.7% respectively. Amounts of 6 coumarin components in 9 samples of angelica dahurica from different localities were processed by cluster analysis and principal component analysis. It was found that the results of cluster analysis and principal component analysis were consistent and the samples could be divided into 3 categories.