采用QuEChERS方法结合气相色谱-串联质谱法测定浆果中7种酰胺类杀菌剂（甲霜灵、呋霜灵、苯霜灵、环酰菌胺、苯酰菌胺、环氟菌胺、噻呋酰胺）残留量。取5.0 g的浆果样品依次用1%（体积分数）乙酸-乙腈溶液20 mL萃取和5 g无水硫酸镁盐析后，萃取液经N-丙基乙二胺、十六烷基硅烷（C₁₈）、石墨化炭黑净化，在6 000 r·min^-1转速下离心；取上清液在60 ℃下氮吹至近干，用正己烷定容至1.0 mL，过0.2 μm滤膜，滤液在DB-5MS色谱柱（30 m×0.25 mm，0.25 μm）、程序升温的条件下进行色谱分离，并在多反应监测（MRM）模式下进行质谱分析，采用内标法定量。7种酰胺类杀菌剂的线性范围均为0.04~4.0 mg·L^-1，检出限（3S/N）为0.001~0.003 mg·kg^-1。对葡萄样品进行3个浓度水平的加标回收试验，测得回收率为86.2%~100%；测定值的相对标准偏差（n=6）为1.6%~4.1%。

An analytical method for determination of 7 residual amount of amide fungicides (metalaxyl, furalaxyl, benalaxyl, fenhexamid, benzoyl amine, cyflufenamidand thifluzamide) in berries by QuEChERS-GC-MS/MS was established in the work. 5.0 g of the berry samples were extracted by 20 mL of 1% (volume fraction) acetic acid-acetonitrile solution, then 5 g anhydrous magnesium sulfate was used to salt out. The extracted solution obtained was purified by N-propyl ethylenediamine, C₁₈ and graphitized carbon black, and centrifuged at 6 000 r·min^-1 rotation speed. The supernatant was taken and evaporated to near-dryness by N₂-blowing at 60℃, and dissolved and diluted to 1.0 mL with n-hexane, then filtered through a 0.2 μm filter membrane. The filtrate was introduced to DB-5MS chromatographic column (30 m×0.25 mm, 0.25 μm) and separated under the programmed temperature elevation, and then analyzed by MS/MS with MRM mode. Internal standard method was used in quantitative analysis. Linearity ranges of 7 amide fungicides were found in the same range of 0.04-4.0 mg·L^-1, with detection limits (3S/N) of 0.001-0.003 mg·kg^-1. Tests for the spiked recovery were made at 3 concentration levels for the grape samples, giving results of recovery ranged from 86.2% to 100%. Values of RSDs (n=6) found were in the range of 1.6%-4.1%.