建立了超声萃取-超高效液相色谱-串联质谱法（UHPLC-MS/MS）测定玩具涂层中2-二甲氨基-2-苄基-1-[4-（4-吗啉基）苯基]-1-丁酮（光引发剂IHT-PI 910）和2-甲基-1-[4-（甲基硫代）苯基]-2-（4-吗啉基）-1-丙酮（光引发剂IHT-PI 907）残留量的方法。用10 mL乙腈在60 ℃下超声提取样品30 min，加入0.1%（体积分数，下同）甲酸溶液，过0.20 μm滤膜，滤液供UHPLC-MS/MS分析。以ACQUITY UPLC BEH C₁₈色谱柱为固定相，不同体积比的乙腈和0.1%甲酸溶液组成的混合溶液为流动相进行梯度洗脱，目标物经色谱分离后，在电喷雾离子源正离子（ESI⁺）模式和多反应监测（MRM）模式下进行质谱分析。结果显示：在优化的试验条件下，2种光引发剂可在3.00 min内完成测定；标准曲线的线性范围均为0.5~100 μg·L^-1，检出限（3S/N）均为1.0 μg·L^-1；对阴性样品进行3个浓度水平的加标回收试验，所得回收率为87.9%~93.4%，测定值的相对标准偏差（n=7）为1.2%~8.6%。用此方法分析了20个随机样品，3个样品检测结果均为阳性，样品2中光引发剂IHT-PI 907的最高检出量为1 528 mg·kg^-1，超出了REACH法规的限量（1 000 mg·kg^-1）要求。

A method for the determination of 2-benzyl-2-(dimethylamino)-4'-morpholinobutyrophenone (IHT-PI 910) and 2-methyl-4'-(methylthio)-2-morpholinopropiophenone (IHT-PI 907) in toy coatings by ultrasonic extraction-ultra high performance liquid chromatography mass spectrometry (UHPLC-MS/MS) was established. The sample was extracted with 10 mL acetonitrile at 60 ℃ for 30 min, then mixed with 0.1% (volume fraction, the same below) formic acid solution and filtered through 0.20 μm membrane. The filtrate obtained was analyzed by UHPLC-MS/MS. ACQUITY UPLC BEH C₁₈ chromatographic column was used as stationary phase, and mixed solution composed of acetonitrile and 0.1% formic acid solution with various volume ratios was used as mobile phase for gradient elution. The targets separated were analyzed with electrospray ion source positive ion (ESI⁺) mode and multiple reaction monitoring (MRM) mode. The results showed that under the optimized test conditions, the two photoinitiators could be determined within 3.00 min; linear ranges of the standard curves of 2 targets found were both 0.5-100 μg·L^-1, with detection limits (3S/N) of 1.0 μg·L^-1; the spiked recovery was made on the negative samples at 3 concentration levels, giving values of recovery ranged from 87.9% to 93.4%, and RSDs (n=7) of determined values were in the range of 1.2%-8.6%. This method was used in the analysis of 20 samples, and photoinitiators were detected in 3 samples, with the maximum detection amount of 1 528 mg·kg^-1 for IHT-PI 907 in No.2 sample, exceeding the limit (1 000 mg·kg^-1) specified by REACH regulation.