建立了气相色谱-串联质谱法测定竹木砧板中五氯酚含量的方法。通过表层取样法与九点式布点法联合制备样品后，在2.00 g样品中加入10.0 mg·L^-1的2，4，6-三溴酚内标溶液50 μL，以体积比1∶9的乙酸乙酯-正己烷混合液10 mL为提取剂，经SLC固相萃取柱净化后，洗脱液氮吹至1.0 mL，用体积比1∶1的乙酸酐-吡啶混合液进行衍生。样品衍生后，在Agilent J&W DB-5MS石英毛细管色谱柱上采用柱升温程序进行分离。质谱分析中采用多反应监测模式检测，内标法定量。结果表明：五氯酚的质量浓度在25~800 μg·L^-1内与五氯酚衍生物和2，4，6-三溴酚衍生物的峰面积比值呈线性关系，检出限（3S/N）为0.003 mg·kg^-1。按标准加入法进行回收试验，测得回收率为86.0%~96.0%，测定值的相对标准偏差（n=5）均小于5.0%。按此方法对80份竹木砧板样品开展食品安全风险专项监测，发现非定型包装竹木砧板中五氯酚高残留量（高达384.350 mg·kg^-1）的风险隐患，为相关部门提供了风险预警。

A method was established for the determination of pentachlorophenol in wooden chopping board by gas chromatography-tandem mass spectrometry (GC-MS/MS). The samples were prepared by the surface sampling method and the nine-point layout method. 2,4,6-tribromophenol internal standard solution of 10.0 mg·L^-1 (50 μL) was added into the sample of 2.00 g, and a mixture of ethyl acetate and n-hexane at volume ratio of 1∶9 (10 mL) was used as the extractant. After purification by SLC solid phase extraction column, the eluent was blown to 1.0 mL with nitrogen, and a mixture of acetic anhydride and pyridine at volume ratio of 1∶1 was used for derivatization. After derivatization, the sample was separated on Agilent J&W DB-5MS quartz capillary column by column temperature program. The mode of multireaction monitoring (MRM) was adopted in MS/MS, and internal standard method was used for quantitative analysis. The results showed that linear relationship between peak area ratio of pentachlorophenol derivative and 2,4,6-tribromophenol derivative and mass concentration of pentachlorophenol was found in the range of 25-800 μg·L^-1, with detection limit (3S/N) of 0.003 mg·kg^-1. Test for recovery was made by standard addition method, giving results in the range of 86.0%-96.0%, and RSDs (n=5) of the determined values less than 5.0%. This method was used to carry out special food safety risk monitoring on 80 samples of wooden chopping board, and the hidden risk of high residues of pentachlorophenol (up to 384.350 mg·kg^-1) in non-shaped packaging wooden chopping boards was discovered, which provided risk early warning for relevant departments.