多孔氧化锆基体上涂覆羟基磷灰石涂层材料的制备和性能
Fabrication and Property of Porous ZrO2 Coated with HA
摘 要
用凝胶成型法制备了三维网状开孔结构的多孔氧化锆(ZrO2)支架材料,通过改变浸渍循环次数实现了对材料孔隙率的控制;然后在多孔ZrO2支架的表面涂覆了羟基磷灰石(HA)涂层,中间涂覆了氟磷灰石(FA)层,用XRD对其进行了表征,并进行了体外模拟试验.结果表明:加入FA中间层以后,防止了HA和ZrO2之间的化学反应,提高了涂层性能;涂覆了HA的多孔ZrO2材料的强度是多孔HA材料强度的7倍多;这种有涂层的多孔支架材料很适合细胞的生长,具有良好的生物相容性.
羟基磷灰石涂层
孔隙率
体外模拟
porous ZrO2
hydroxyapatite coating
porosity
vitro cellular assay
Abstract
ZrO2 porous scaffolds with three-dimensional opening mesh structure were fabrication first by shaping gel method which could cntroll the porosity could by changing the dipping cycles.Then HA coatings were coated on the porous ZrO2 scaffolds with a layer of fluorapatite (FA) as intermediate layer.The as-prepared coatings were characterized by XRD and simulated in vitro.The results show that FA intermediate layer could prevent the chemical reactions between ZrO2 and HA and raise the performance of the coating.The strength of the porous ZrO2 coated with HA was over 7 times of that of the pure porous HA materials.The prepared coating is suitable for cell growth and has good biocompatibility.
中图分类号 TG146.1
所属栏目 试验研究
基金项目
收稿日期 2007/11/1
修改稿日期 2008/10/20
网络出版日期
作者单位点击查看
备注王莉丽(1974-),女,陕西咸阳人,硕士,讲师.
引用该论文: WANG Li-li,WANG Xiu-feng,JIANG Hong-tao,YU Cheng-long. Fabrication and Property of Porous ZrO2 Coated with HA[J]. Materials for mechancial engineering, 2008, 32(12): 5～7
王莉丽,王秀峰,江红涛,于成龙. 多孔氧化锆基体上涂覆羟基磷灰石涂层材料的制备和性能[J]. 机械工程材料, 2008, 32(12): 5～7
被引情况:
【1】熊峰,彭如恕, "预烧结温度对多孔氧化锆陶瓷孔隙率和力学性能的影响",机械工程材料 40, 23-26(2016)
共有人对该论文发表了看法，其中：
人认为该论文很差
人认为该论文较差
人认为该论文一般
人认为该论文较好
人认为该论文很好
参考文献
【1】姚秀敏,谭寿洪,江东亮.孔径可控的多孔羟基磷灰石的制备工艺研究[J].功能材料与器件学报,2001(6):152-156.
【2】Liu D M,Troczynski T,Tseng W J.Water-based sol-gel synthesis of hydroxyapatite:process development[J].Biomaterials,2001,22:1721-1730.
【3】Guo Hongbo,Khor Khiam Aik,Boey Yin Chiang,et al.Laminated and functionally graded hydroxyapatite/ yttria stabilized trtragonal zirconia composites fabricated by spark plasma sintering[J].Biomaterials,2003,24:667-675.
【4】Kasten P,Luginbuhl R,van Griensven M,et al.Comparison of human bone marrow stromal cells seeded on calcium-defincient gydroxyapatite,-tricalcium phosphate and demineralized bone matrix[J].Biomaterical,2003,24:2593-2603.
【5】Lima V J P,Khora K A,Fua L,et al.Hydroxyapatite±zirconia composite coatings via the plasma spraying process[J].Journal of Materials Processing Technology,1999,90:491-496.
【6】Chou Bang-Yen,Chang Edward.Interface investigation of plasma-sprayed hydroxyapatite coating on titanium alloy with ZrO2 intermediate layer as bond coat[J].Scripta Materialia,2001,45:487-493.
【2】Liu D M,Troczynski T,Tseng W J.Water-based sol-gel synthesis of hydroxyapatite:process development[J].Biomaterials,2001,22:1721-1730.
【3】Guo Hongbo,Khor Khiam Aik,Boey Yin Chiang,et al.Laminated and functionally graded hydroxyapatite/ yttria stabilized trtragonal zirconia composites fabricated by spark plasma sintering[J].Biomaterials,2003,24:667-675.
【4】Kasten P,Luginbuhl R,van Griensven M,et al.Comparison of human bone marrow stromal cells seeded on calcium-defincient gydroxyapatite,-tricalcium phosphate and demineralized bone matrix[J].Biomaterical,2003,24:2593-2603.
【5】Lima V J P,Khora K A,Fua L,et al.Hydroxyapatite±zirconia composite coatings via the plasma spraying process[J].Journal of Materials Processing Technology,1999,90:491-496.
【6】Chou Bang-Yen,Chang Edward.Interface investigation of plasma-sprayed hydroxyapatite coating on titanium alloy with ZrO2 intermediate layer as bond coat[J].Scripta Materialia,2001,45:487-493.
相关信息
